Market Definition:
• Epigenetics is referred to all molecular pathways modulating the expression of a genotype into a particular phenotype. Epigenetics consistently indicates changes that affect gene activity and expression, but it can also be used to illustrate any heritable phenotypic change.
• It is mainly a study of change in the gene expression without any change in gene sequence. Some of the examples consists of activating changes namely histone acetylation and DNA demethylation, repressive changes like DNA methylation and histone modifications influenced by noncoding RNAs, such as microRNA and long noncoding RNA.
Market Overview and Trends
• There are various epigenetic drugs developed and in clinical trials for aiming at histone deacetylation and DNA methylation enzymes.
• The factor which is predicted to further drive the expansion is the organizations, for example, the National Cancer Institute (NCI), the International Human Epigenome Consortium (IHEC) and the National Institute of Health (NIH) which encourage funding and support to R&D and product development exercises applicable to the field of epigenetics.
• Epigenetics research is paying particular attention to the discovery of treatment options for various types of tumours. The International Cancer Genome Consortium (ICGC) is focusing on acquiring the epigenomic changes, transcriptomic changes and genomic description in different types of tumours.
• With an objective to distinguish all the human genome sequence functional elements the Encyclopaedia of DNA Elements (ENCODE) project was launched by the U.S. National Human Genome Research Institute.
Market Dynamics:
Factors Influencing the Market Growth:
• Increasing frequency of cancer and other chronic diseases and growing geriatric population are some of the key factors predicted to drive the market.
• The factors driving the growth of this market is advancements in screening tools, rising incidence of cancer and huge amounts invested in research and development activities.
• The demand for epigenetic diagnosis and drugs is expected to increase due to the increase in ageing population and rising incidence of oncology and non- oncology disorders.
• Some of the factors contributing to fuelling the growth of the global epigenetics market are the increasing number of retail clinics, companion diagnostics and development of entire genome technology.
• The market is also driven by the increase in research and developmental activities which helps in expanding facilities in various fields such as clinical and pharmaceutical research.
Factors Restraining the Market Growth:
• The growth of epigenetic market is likely to be hampered by the lack of funds from the government and high cost of the procedures and consumers do not wish to invest in such expensive products, especially research groups with limited budgets and funding.
Market Segmentation 2019-2029:
The Epigenetics Diagnostic market is segmented on the product, technology, application and region.
1. Epigenetics Diagnostic, by Product
a) Reagents
b) Kits
– ChIP Sequencing Kit
– Whole Genomic Amplification Kit
– Bisulfite Conversion Kit
– RNA Sequencing Kit
– Others
c) Instruments
d) Enzymes
e) Services
2. Epigenetics Diagnostic, by Technology
a) DNA Methylation
– Reagents
– Kits
– Instruments
– Enzymes
– Services
b) Histone Methylation
– Reagents
– Kits
-Instruments
– Enzymes
– Services
c) Histone Acetylation
– Reagents
– Kits
– Instruments
– Enzymes
– Services
d) Large non-coding RNA
– Reagents
– Kits
– Instruments
-Enzymes
– Services
e) MicroRNA Modification
– Reagents
– Kits
– Instruments
– Enzymes
– Services
f) Chromatin structures
– Reagents
– Kits
– Instruments
– Enzymes
– Services
3. Epigenetics Diagnostic, by Application
a) Oncology
– Solid Tumours
– Liquid Tumours
b) Non-oncology
– Inflammatory Diseases
– Metabolic Diseases
– Infectious Diseases
– Cardiovascular Diseases
– Others
4. Epigenetics Diagnostic, by Region
a) North America
– US
– Canada
b) Europe
– Germany
– UK
– France
– Rest of Europe
c) Asia Pacific
– Japan
– China
– India
– Rest of Asia Pacific
d) Rest of the World (RoW)
Competitive Analysis:
• Research and development is the primary strategy adopted by the key players in the Global Biodefense market.
• These companies have developed various strategies and developments such as product launch, partnerships, mergers & acquisitions, joint venture, and collaborations.
Major Market Players:
Celgene Corporation, CellCentric Ltd, Chroma Therapeutics Ltd, Covaris Inc, DIAGENODE, INC., Ribimed Biotechnologies, Epigenomics AG, Epitherapeutics, Epizyme, Karus Therapeutics, Merck Millipore, Novartis International AG, Oncolys Biopharma Inc, OncoMethylome Sciences, Qiagen, Sigma-Aldrich Corporation, Syndax Pharmaceuticals and ZYMO RESEARCH CORPORATION (ZYMO).
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CCR Ref number: KD4R6
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1. Introduction
1.1 Objectives of the Study
1.2 Market Definition
1.3 Market Scope
1.3.1 Markets Covered
1.3.2 Years Considered for the Study
1.4 Stakeholders
2. Research Methodology
2.1 Research Data
2.1.1 Primary Data
2.1.2 Secondary Data
2.2 Market Size Estimation
2.3 Research Assumptions
3. Executive Summary
4. Industry Insights
5. Epigenetics Diagnostic market – By Product
5.1 Reagents
5.2 Kits
5.2.1 ChIP Sequencing Kit
5.2.2 Whole Genomic Amplification Kit
5.2.3 Bisulfite Conversion Kit
5.2.4 RNA Sequencing Kit
5.2.5 Others
5.3 Instruments
5.4 Enzymes
5.5 Services
6. Epigenetics Diagnostic market – By Technology
6.1 DNA Methylation
6.1.1 Reagents
6.1.2 Kits
6.1.3 Instruments
6.1.4 Enzymes
6.1.5 Services
6.2 Histone Methylation
6.2.1 Reagents
6.2.2 Kits
6.2.3 Instruments
6.2.4 Enzymes
6.2.5 Services
6.3 Histone Acetylation
6.3.1 Reagents
6.3.2 Kits
6.3.3 Instruments
6.3.4 Enzymes
6.3.5 Services
6.4 Large non-coding RNA
6.4.1 Reagents
6.4.2 Kits
6.4.3 Instruments
6.4.4 Enzymes
6.4.5 Services
6.5 MicroRNA Modification
6.5.1 Reagents
6.5.2 Kits
6.5.3 Instruments
6.5.4 Enzymes
6.5.5 Services
6.6 Chromatin structures
6.6.1 Reagents
6.6.2 Kits
6.6.3 Instruments
6.6.4 Enzymes
6.6.5 Services
7. Epigenetics Diagnostic, by Application
7.1 Oncology
7.1.1 Solid Tumours
7.1.2 Liquid Tumours
7.2 Non-oncology
7.2.1 Inflammatory Diseases
7.2.2 Metabolic Diseases
7.2.3 Infectious Diseases
7.2.4 Cardiovascular Diseases
7.2.5 Others
8. Epigenetics Diagnostic Market – By Region
8.1 North America
8.1.1 US
8.1.2 Canada
8.2 Europe
8.2.1 Germany
8.2.2 France
8.2.3 UK
8.2.4 Rest of Europe
8.3 Asia-Pacific
8.3.1 Japan
8.3.2 China
8.3.3 India
8.3.4 Rest of APAC
8.4 LAMEA
8.4.1 Latin America
8.4.2 Middle East
9. Africa Competitive Landscape
10. Company Profiles
10.1 Alnylam Pharmaceuticals Inc.
10.2 Bavarian Nordic.
10.3 Cleveland BioLabs.
10.4 DynPort Vaccine Company LLC.
10.5 Elusys Therapeutics Inc.
10.6 Emergent BioSolutions Inc.
10.7 Ichor Medical Systems.
10.8 Ology Bioscience.
10.9 PharmAthene Inc.
10.10 SIGA Technologies Industries Ltd.
10.11 Other Players
11. Appendix
List of Tables
Table 1 Global Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR%), 2019-2029
Table 2 Global Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 3 Global Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 4 Global Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Region, (US$ Mn AGR%, CAGR%), 2019-2029
Table 5 North America Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2029
Table 7 North America Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 8 North America Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 9 U.S. Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR%), 2019-2029
Table 10 U.S. Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 11 U.S. Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 12 Canada Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2029
Table 13 Canada Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 14 Europe Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 15 Europe Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2029
Table 16 Germany Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 17 France Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 18 UK Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR%), 2019-2029
Table 19 Rest of Europe Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 20 Rest of Europe Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 21 Asia-Pacific Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2029
Table 22 Asia-Pacific Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 23 Japan Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 24 Japan Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR%), 2019-2029
Table 25 China Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 26 China Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 27 India Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR%), 2019-2029
Table 28 India Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 29 Rest of APAC Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 30 Rest of APAC Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2029
Table 31 LAMEA Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 32 LAMEA Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 33 Latin America Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2029
Table 34 Latin America Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 35 Middle East Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 36 Middle East Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2029
Table 37 Africa Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2029
Table 39 Africa Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2029
Table 40 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2030
Table 41Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2031
Table 42 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2032
Table 43 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2033
Table 44 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2034
Table 45 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2035
Table 46 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2036
Table 47 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2037
Table 48 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2038
Table 49 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2039
Table 50 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2040
Table 51 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2041
Table 52 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2042
Table 53 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2043
Table 54 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2044
Table 55 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Product, (US$ Mn AGR%, CAGR %), 2019-2045
Table 56 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Technology, (US$ Mn AGR%, CAGR %), 2019-2046
Table 57 Epigenetics Diagnostic Market Revenue Analysis & Forecast, By Application, (US$ Mn AGR%, CAGR %), 2019-2047
List of Figures
Figure 1 Global Pulmonary Arterial Hypertension Market: Segmentation
Figure 2 Global Pulmonary Arterial Hypertension Market: Research Design
Figure 3 Global Pulmonary Arterial Hypertension Market: Figure 3 Drivers, Restraints, Opportunities, and Challenges
Figure 4 Global Pulmonary Arterial Hypertension Market: By Product
Figure 5 Global Pulmonary Arterial Hypertension Market: By Technology
Figure 6 Global Pulmonary Arterial Hypertension Market: By Application
Figure 6 Global Pulmonary Arterial Hypertension Market: By Region
Figure 7 North America Pulmonary Arterial Hypertension Market: Market Snapshot
Figure 8 Europe Pulmonary Arterial Hypertension Market: Market Snapshot
Figure 9 Asia-Pacific Pulmonary Arterial Hypertension Market: Market Snapshot
Figure 10 LAMEA Pulmonary Arterial Hypertension Market: Market Snapshot
Figure 11 Celgene Corporation diagenode inc: Financial Snapshot
Figure 12 CellCentric Ltd.: Financial Snapshot
Figure 13 Chroma Therapeutics Ltd.: Financial Snapshot
Figure 14 Covaris Inc: Financial Snapshot
Figure 15 Diagenode Inc.: Financial Snapshot
Figure 16 Ribimed Biotechnologies: Financial Snapshot
Figure 17 Epigenomics AG: Financial Snapshot
Figure 18 Epitherapeutics: Financial Snapshot
Figure 19 Epizyme: Financial Snapshot
Figure 20 Karus Therapeutics: Financial Snapshot