Industries > Pharma > Global Translational Regenerative Medicine Market Prospects 2017-2027
Global Translational Regenerative Medicine Market Prospects 2017-2027
Stem Cell Therapies, Tissue Engineered Products, Gene Therapies
The translational regenerative medicine market has been undergoing considerable changes over the last few years. There are a number of therapies that have been launched into the market over the last few years. Stem cell therapies are being developed constantly and these are targeted at various indications, from the more common cardiovascular conditions to rarer orphan indications.
The Global Translational Regenerative Medicine market is expected to grow significantly over the forecast period. The Global Translational Regenerative Medicine market was valued at $5.8bn in 2016. Visiongain forecasts this market to increase to $14.5bn in 2021. The market is estimated to grow at a CAGR of 19.9% in the first half of the forecast period and 17.7% from 2016 to 2027.
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Report Scope
• Global Translational Regenerative Medicine market forecasts from 2017-2027
• Translational Regenerative Medicine regional market forecasts from 2017-2027, covering:
– United States
– Europe
– Asia-Pacific
– Rest of the World
• Global Translational Regenerative Medicine submarket forecasts from 2017-2027 covering:
– Stem Cell Therapies
– Tissue Engineered Products
– Gene Therapies
• Forecasts from 2017-2027 of the leading products in the Global Translational Regenerative Medicine market:
– Osteocel Plus
– Trinity ELITE
– TEMCELL /Prochymal
– Apligraf
– Dermagraft
– Epifix
– ReCell
– Neovasculgen
– Glybera (alipogene tiparvovec)
– IMLYGIC (talimogene laherparepvec)
• Assessment of the leading companies in the Global Translational Regenerative Medicine market:
– Alphatec Spine
– Anterogen
– Athersys
– Avita Medical
– AxoGen
– Medipost
– Mesoblast
– NuVasive
– Ocata Therapeutics
– Organogenesis
– Osiris Therapeutics
– Pharmicell
– Regenerys
– TiGenix
– UniQure
– Vericel Corporation
• SWOT and Porter’s Five Force analysis of the translational regenerative medicine market
Visiongain’s study is intended for anyone requiring commercial analyses for the Translational Regenerative Medicine Market and leading companies. You find data, trends and predictions.
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1. Report Overview
1.1 Global Translational Regenerative Medicine: Market Overview
1.2 Global Translational Regenerative Medicine Market Definition and Segmentation
1.3 Why You Should Read This Report
1.4 How This Report Delivers
1.5 Key Questions Answered By This Analytical Report
1.6 Who Is This Report For?
1.7 Methodology
1.8 Frequently Asked Questions (FAQ)
1.9 Associated Reports
1.10 About Visiongain
2. An Introduction to Translational Regenerative Medicine
2.1 What Is Regenerative Medicine?
2.1.1 Translational Regenerative Medicine – From Bench to Bedside
2.2 Translational Regenerative Medicine – Market Breakdown
2.2.1 Stem Cell Therapy – Marketable Differentiation and Specialization
2.2.1.1 How Embryonic Stem Cells (ESCs) Entered the Fray
2.2.1.2 Classifying Stem Cells by Potency
2.2.1.3 Stem Cells Categories: ESCs, SSCs, iPSCs
2.2.1.4 Parthenogenetic Stem Cells: Ethical ESC-Like Cells?
2.2.1.5 Autologous vs. Allogeneic Stem Cells: Towards Universal Stem Cell Products?
2.2.2 Tissue Engineering – In Vitro Manipulation for Therapeutic Purposes
2.2.3 Gene Therapies
2.2.3.1 Harnessing Infectivity: Viral Vectors in Gene Therapy
2.3 Other Approaches to Regenerative Medicine
2.3.1 Small Molecules and Proteins – Scaffold-Based Delivery of Signaling Molecules
2.3.2 Cosmetic Applications of Regenerative Medicine
2.4 Regulation of Regenerative Medicine
2.4.1 Regulation of Regenerative Medicine Products in Europe
2.4.2 Regulation of Regenerative Medicine Products in the US
2.5 The Phases of Clinical Trials
2.6 Market Definition
2.6.1 Products Excluded from the Report
3. Translational Regenerative Medicine Market, 2017-2027
3.1 Global Translational Regenerative Medicine: Market Overview
3.1.1 Segments within the Global Translational Regenerative Medicine Market
3.2 The Global Translational Regenerative Medicine Market in 2016 and 2017
3.3 Global Translational Regenerative Medicine: Market Forecast 2017-2027
3.3.1 Market Sectors That Will Drive Translational Regenerative Medicine Growth
3.3.2 Global Translational Regenerative Medicine Market - Changing Market Shares by Sector 2017-2027
3.3.3 Global Translational Regenerative Medicine Market – Current Developments in the field, 2016 & 2017
3.3.4 Global Translational Regenerative Medicine Market – Current Advancement in the field, 2016 & 2017
3.3.5 Global Translational Regenerative Medicine Market – Current Key Approvals in the field, 2017
4. Stem Cell Therapies: Leading Applications, 2017-2027
4.1 The Global Market for Stem Cell Therapies, 2016 and 2017
4.1.1 Stem Cell Therapies: Currently Available Therapies
4.1.2 Haematopoietic Stem Cell Transplantation (HSCT)
4.1.2.1 HSCT for the Treatment of Multiple Sclerosis – A Possible Cure?
4.1.3 Stem Cell Orthobiologics
4.2 Stem Cell Therapies: Global Market Forecast 2017-2027
4.3 AlloStem (AlloSource)
4.4 Osteocel Plus (NuVasive)
4.4.1 Osteocel Plus: Sales Forecast 2017-2027
4.5 Trinity ELITE and Trinity Evolution (Orthofix)
4.5.1 Trinity ELITE and Trinity Evolution: Sales Forecast, 2017-2027
4.6 PureGen (AlphaTec Spine)
4.7 Other Approved Stem Cell Therapy Products, 2015
4.7.1 Cartistem (Medipost)
4.7.2 Cupistem (Anterogen)
4.7.3 Hearticellgram-AMI (Pharmicell)
4.7.4 TEMCELL/ Prochymal/ Remestemcel-L (Mesoblast)
4.7.4.1 TEMCELL/ Prochymal (Remestemcel-L): Sales Forecast 2017-2027
4.8 Development Pipeline for Stem Cell Therapies, 2017-2027
4.8.1 Late-Stage Pipeline for Stem Cell Therapies, 2015
4.8.1.1 StemEx and NiCord (Gamida Cell)
4.8.1.1.1 StemEx Shows Improved Survival at 100 Days – but FDA Wants Another Clinical Trial
4.8.1.2 Copper Chelator Based Technology
4.8.1.3 NiCord
4.8.1.3.1 NiCord: Gamida Cell Reaches Agreement on Phase 3 Design Outline with the FDA and EMA
4.8.1.3.2 NAM Technology Platform
4.8.1.4 Mesenchymal Precursor Cell Therapies (Mesoblast)
4.8.1.5 Adult Autologous CD34+ Cells (Baxter)
4.8.1.6 MyoCell (U.S. Stem Cell Inc.)
4.8.1.7 Adipocell (Bioheart)
4.8.1.8 Cx601 (TiGenix)
4.8.1.9 Adipose-Derived Stem Cells (Cytori Therapeutics)
4.8.1.10 Stempeucel (Stempeutics Research)
4.8.1.11 C-Cure (Cardio3 BioSciences)
4.8.1.12 Other Late-Stage Stem Cell Therapies
4.8.2 Diabetes and Stem Cell Therapy
4.8.2.1 Mesenchymal Precursor Cells (Mesoblast)
4.8.2.2 VC-01 (ViaCyte Inc)
4.8.2.2.1 Clinical Development Efforts for VC-01 for the Treatment of Diabetes
4.8.3 Cardiovascular Disease and Stem Cell Therapy
4.8.3.1 Endometrial Regenerative Cells (MediStem, Intrexon)
4.8.3.2 AMR-001 (Caladrius Biosciences)
4.8.3.3 CAP-1002 (Capricor)
4.8.4 Stem Cell Therapy in Cancer
4.8.4.1 CLT-008 (Cellerant Therapeutics)
4.8.4.2 OncoCyte/BioTime – Targeting Cancer with Gene and Stem Cell Therapy
4.8.5 Stem Cell Therapy for Central Nervous System (CNS) Conditions
4.8.5.1 NurOwn (BrainStorm Cell Therapeutics)
4.8.5.1.1 Clinical Development Efforts for NurOwn, 2015
4.8.5.2 NSI-566 (Neuralstem)
4.8.5.3 NSI-189 (Neuralstem)
4.8.5.4 MultiStem (Athersys)
4.8.5.5 PDA-001 (Cenplacel-L, Celgene)
4.8.5.6 ALD-401 (Cytomedix)
4.8.5.7 ReN001 (ReNeuron)
4.8.6 Stem Cell Therapy for Eye Diseases
4.8.6.1 MA09-hRPE (Ocata Therapeutics)
4.8.6.2 HuCNS-SC (StemCells Inc.)
4.8.6.3 Collaboration and License Agreement Between Pfizer And The London Project to Cure Blindness
4.9 ChondroCelect (TiGenix BV)
4.10 Stem Cells Therapy Market: Drivers and Restraints 2017-2027
5. Tissue Engineering Therapies: Leading Applications, 2017-2027
5.1 The Global Market for Tissue Engineered Therapies, 2016
5.1.1 Tissue Engineering Therapies: Currently Available Therapies
5.2 Tissue Engineering Therapies: Global Market Forecast 2017-2027
5.3 Tissue Engineering in Wound Repair and Healing
5.3.1 Apligraf (Organogenesis)
5.3.1.1 Apligraf: Historical Sales Analysis
5.3.1.2 Apligraf: Sales Forecast 2017-2027
5.3.2 BioDfence and BioDfactor (BioD)
5.3.3 CureXcell (MacroCure)
5.3.4 Dermagraft (Organogenesis)
5.3.4.1 Dermagraft (Organogenesis): Sales Forecast 2017-2027
5.3.5 Epifix (MiMedx)
5.3.5.1 Epifix (MiMedx): Sales Forecast 2017-2027
5.3.6 Epicel (Vericel)
5.3.7 Grafix (Osiris Therapeutics)
5.3.8 MySkin and CyroSkin (Regenerys)
5.3.9 ReCell (Avita Medical)
5.3.9.1 ReCell (Avita Medical): Sales Forecast 2017-2027
5.4 Tissue Engineering for Cartilage Repair
5.4.1 Autologous Chondrocyte Implantation (ACI)
5.4.2 Carticel (Vericel Corp.)
5.4.3 ChondroCelect (TiGenix, Sobi Partners)
5.4.4 DeNovo NT (Zimmer)
5.4.5 MACI (Vericel Corp.)
5.5 Other Available Tissue Engineering Therapies
5.5.1 Autologous Cultured Cell and Tissue Products (Japan Tissue Engineering Co.)
5.5.2 Gintuit (Organogenesis)
5.5.3 LAVIV (azficel-T), (Fibrocell Science)
5.5.4 Acellular Tissue Engineering Products
5.6 Tissue Engineering: Development Pipeline, 2017-2027
5.6.1 Pipeline Products for Autologous Chondrocyte Implantation
5.6.2 Tissue Engineering for Skin
5.6.3 Tissue Engineering for Liver Diseases
5.6.3.1 Extracorporeal Bio-Artificial Liver Therapy (Vital Therapies)
5.6.4 Tissue Engineering for Cardiovascular Disease
5.6.5 Tissue Engineering for Eye Diseases
5.7 Future Prospects for Organ Transplantation and Tissue Engineering
5.8 Tissue Engineered Products Market: Drivers and Restraints 2017-2027
6. Gene Therapies: Leading Applications, 2017-2027
6.1 The Global Market for Gene Therapies, 2016
6.2 Gene Therapies: Global Market Forecast 2017-2027
6.3 Currently Available Gene Therapy Products
6.3.1 Gendicine (Benda Pharmaceutical)
6.3.2 Oncorine (Shanghai Sunway Biotech)
6.3.3 Neovasculgen (Human Stem Cells Institute)
6.3.3.1 Neovasculgen (HSCI): Sales Forecast 2017-2027
6.3.4 Glybera (UniQure)
6.3.4.1 Glybera: Sales Forecast 2017-2027
6.3.5 IMLYGIC (talimogene laherparepvec) – (Amgen)
6.3.5.1 Clinical Trials and Development Efforts for IMLYGIC
6.3.5.2 Talimogene Laherparepvec (IMLYGIC) – Sales Forecast 2017-2027
6.4 Development Pipeline for Gene Therapies, 2017-2027
6.4.1 Late-Stage Pipeline Gene Therapies, 2015
6.4.1.1 Collategene (beperminogene perplasmid, AMG0001) - (AnGes MG/Vical)
6.4.1.2 ProstAtak (AdV-tk) - (Advantagene)
6.4.1.3 Trinam (taberminogene vadenovec) – (Ark Therapeutics)
6.4.1.4 AAV2-hRPE65v2 (Spark Therapeutics)
6.4.1.5 CG0070 (Cold Genesys)
6.4.2 Gene Therapy for Use in the Treatment of Diabetes
6.4.3 Gene Therapy Directed At Oncology Indications
6.4.4 Gene Therapy Directed at Neurological Diseases
6.4.5 Gene Therapy Directed at Tackling Haemophilia B
6.5 Gene Therapy Market: Drivers and Restraints 2017-2027
7. Leading National Markets for Translational Regenerative Medicine, 2017-2027
7.1 The Translational Regenerative Medicine Market by Region
7.1.1 The Global Distribution of Translational Regenerative Medicine in 2016 and 2017
7.2 Leading National Markets: Forecast 2017-2027
7.2.1 Changing Market Shares by Region, 2017-2027
7.3 Regional Translational Regenerative Medicine Markets: Analysis and Forecasts, 2017-2027
7.4 United States: The Largest Translational Regenerative Medicine Market
7.4.1 US Translational Regenerative Medicine Market: Market Drivers and Restraints, 2017-2027
7.4.2 US Translational Regenerative Medicine Market: Market Forecast 2017-2027
7.4.3 The Regulatory Framework for Regenerative Medicine in the US
7.4.4 The Impact of Ethical and Regulatory Reluctance to Embryonic Stem Cell Research and Its Impact on Funding
7.4.5 How Is the Ending of Patenting for Human Gene Products Affecting the Regenerative Medicine Market in the US?
7.5 Europe: A Fragmented Regenerative Medicine Market
7.5.1 European Regenerative Medicine Market: Market Drivers and Restraints, 2017-2027
7.5.2 European Regenerative Medicine Market: Market Forecast 2017-2027
7.5.3 Europe’s Unitary Patent System and Its Impact on the Future of Regenerative Medicine in the Region
7.5.4 Regulation of Regenerative Medicine in the European Union
7.5.5 UK: A Leading Research Centre for Regenerative Medicine in Europe
7.5.5.1 Regulation of Stem Cell Research in the UK
7.5.6 Russia: Rising Interest in Regenerative Medicine Research
7.6 Asia-Pacific: Accommodating Regulatory Landscape Aiding Rapid Product Commercialisation
7.6.1 Asia-Pacific Regenerative Medicine Market: Market Drivers and Restraints, 2017-2027
7.6.2 Asia-Pacific Regenerative Medicine Market: Market Forecast 2017-2027
7.6.3 Australia: Encouraging Translational Regenerative Medicine
7.6.4 China: Encouraging Stem Cell R&D
7.6.4.1 Government Intervention into TRM Research in China
7.6.4.2 Regulation of Stem Cell Research in China
7.6.4.3 Commercialisation of Gene Therapy and Tissue Engineering Products in China
7.6.4.4 Medical Tourism Impacting Market Growth for Regenerative Medicine in China
7.6.5 Japan: Difficulty in Translating Research into Commercialisation
7.6.5.1 Research Funding: A Major Determinant of Growth in Japan’s Regenerative Medicine
7.6.5.2 Government Interventions in Promoting Stem Cell Research in Japan
7.6.5.3 Regulation of Regenerative Medicine in Japan
7.6.5.4 Accelerating Approvals of Regenerative Medicine Products in Japan
7.6.6 India: An Emerging Market for Regenerative Medicine
7.6.6.1 Efforts in Stem Cell Research in India
7.6.6.2 Unclear Guidelines Hindering Progression of Gene Therapy Research in India
7.6.7 South Korea: First to Approve Stem Cell Treatments
7.6.7.1 A Regeneration In South Korea’s Stem Cell Research Efforts
7.7 Rest of the World: Regenerative Medicine Conquering New Territories and Booming
7.7.1 Rest of the World Regenerative Medicine Market: Market Forecast 2017-2027
8. Leading Companies in the Translational Regenerative Medicine Market, 2017-2027
8.1 Translational Regenerative Medicine: A Hotbed for Innovation
8.2 Alphatec Spine
8.2.1 Alphatec Spine: Financial and Performance Analysis, 2011-2015
8.2.2 Alphatec Spine’s Shifting Focus from Regenerative Medicine to Medical Devices
8.3 Anterogen
8.3.1 Anterogen: Pipeline Analysis, 2015
8.4 Athersys
8.4.1 Athersys: Financial and Performance Analysis, 2011-2015
8.4.2 Athersys: Pipeline Analysis, 2015
8.4.2.1 MultiStem Technology – Potential Treatment for a Range of Diseases
8.5 Avita Medical
8.5.1 Avita Medical: Historical Financial and Performance Analysis, 2013-2015
8.5.2 Avita Medical: Regenerative Medicine Portfolio, 2015
8.5.3 Avita Medical: Pipeline Analysis, 2015
8.6 AxoGen
8.6.1 AxoGen: Historical Financial and Performance Analysis, 2011-2015
8.6.2 AxoGen: Regenerative Medicine Portfolio, 2015
8.6.3 AxoGen: Pipeline Analysis, 2015
8.7 Medipost
8.7.1 Medipost: Historical Financial and Performance Analysis, 2011-2015
8.7.2 Medipost: Regenerative Medicine Portfolio, 2015
8.7.3 Medipost: Pipeline Analysis, 2015
8.8 Mesoblast
8.8.1 Mesoblast Product Portfolio, 2015
8.8.2 Mesoblast: Historical Financial and Performance Analysis, 2010-2015
8.8.3 Mesoblast: Pipeline Analysis, 2015
8.8.3.1 NeoFuse
8.8.3.2 Chondrogen
8.8.3.3 Prochymal / TEMCELL
8.8.3.4 Other Recent Pipeline Acquisitions by Mesoblast
8.9 NuVasive
8.9.1 NuVasive Product Portfolio, 2015
8.9.2 NuVasive: Historical Financial and Performance Analysis, 2011-2015
8.9.3 NuVasive: Pipeline Analysis, 2015
8.10 Ocata Therapeutics (Acquired by Astellas Pharma Inc.)
8.10.1 Ocata Therapeutics: Historical Financial and Performance Analysis, 2011-2015
8.10.2 Ocata Therapeutics: Pipeline Analysis, 2015
8.10.2.1 Retinal Pigment Epithelial Cell Therapy
8.10.3 Ocata’s Other Therapeutic Platforms
8.11 Organogenesis
8.11.1 Organogenesis RM Portfolio, 2015
8.11.2 Organogenesis: Pipeline Analysis, 2015
8.12 Osiris Therapeutics
8.12.1 Osiris Therapeutics: RM Portfolio, 2015
8.12.2 Osiris Therapeutics: Historical Financial and Performance Analysis, 2011-2015
8.12.3 Osiris Therapeutics: Pipeline Analysis, 2015
8.13 Pharmicell
8.13.1 Pharmicell: Historical Financial and Performance Analysis, 2011-2015
8.13.2 Pharmicell: Pipeline Analysis, 2015
8.14 Regenerys
8.14.1 Regenerys: RM Portfolio, 2015
8.14.2 Regenerys: Pipeline Analysis, 2015
8.15 TiGenix
8.15.1 TiGenix: Historical Financial and Performance Analysis, 2011-2015
8.15.2 TiGenix: Pipeline Analysis, 2015
8.16 UniQure
8.16.1 UniQure: Recent Major Acquisition and Collaboration
8.16.2 UniQure: Pipeline Analysis, 2015
8.17 Vericel Corporation (Formerly Aastrom Biosciences, Inc.)
8.17.1 Vericel’s Acquisition of Sanofi’s Regenerative Medicine Business
8.17.2 Vericel: Historical Financial and Performance Analysis, 2011-2015
8.17.3 Vericel Regenerative Medicine Portfolio, 2015
8.18.4 Vericel: Pipeline Analysis, 2015
8.17.2.1 The ixCELL-DCM Clinical Trial
9. Qualitative Analysis for the Global Translational Regenerative Medicine Market, 2017-2027
9.1 Market Factors Influencing the Translational Regenerative Medicine Market
9.2 SWOT Analysis of the Translational Regenerative Medicine Market, 2017-2027
9.3 Strengths
9.3.1 Improvements in Regulatory Frameworks
9.3.2 Advancements in General Cellular and Tissue Research Aiding Regenerative Medicine
9.3.3 Strong Support from Governments in Multiple Regions
9.3.4 Increasing Ease of Product Commercialisation and Market Access
9.4 Weaknesses
9.4.1 The High Price of Translational Regenerative Medicine Products May Restrain Market Growth
9.4.2 Lack of Funding from Venture Capital
9.4.3 The Intrinsic Lack of Standardisation is a Burden to Scaling up Manufacturing
9.4.4 Successful Commercialisation of TRM Products Requires New Business Models
9.5 Opportunities
9.5.1 3D Bioprinting and Other Technologies May Enable Rapid Scale-Up
9.5.2 Medical Tourism May Stimulate Standardisation and Drive Market Growth
9.5.3 Disruptive Translational Regenerative Medicine Therapies Can Create New Markets
9.6 Threats
9.6.1 Ethical Concerns Limiting R&D in Regenerative Medicine
9.6.2 Difficulty Establishing an Evidence Base For Long-Term Efficacy Of TRM Therapies
9.6.3 Rate of Scientific Progress – A Major Determinant of TRM Market Growth
9.6.4 Restraints on Reimbursement May Slow Growth
9.7 Porter’s Five Force Analysis of the Translational Regenerative Medicine Market, 2017-2027
9.7.1 Threat of New Entrants
9.7.2 Threat of Substitutes
9.7.3 Power of Suppliers
9.7.4 Power of Buyers
9.7.5 Rivalry among Competitors
10. Conclusions
10.1 Overview of Current Market Conditions and Market Forecast, 2017-2027
10.2 Leading Regenerative Medicine Segments in 2016 and 2017
10.3 Leading Regions in the Translational Regenerative Medicine Market in 2016 And 2017
10.4 Future Outlook for the Various Sectors within TRM, 2017-2027
10.5 R&D Pipeline Products Crucial to Future Market Growth
10.6 What Does the Future Hold for Regenerative Medicine?
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List of Tables
Table 1.1 (Sample) Global Translational Regenerative Medicine Market: Market Forecast ($m, AGR% and CAGR%) by Segment, 2016-2021
Table 2.1 European Union Definitions of Regenerative Medicine Products, 2015
Table 2.2 Potency and Source of Stem Cells, 2016
Table 2.3 Germ Layers and Their Associated Types of Cells and Organs, 2016
Table 2.4 Major Types of Stem Cells and Their Properties, 2016
Table 2.5 Terminology for Stem Cell Donor-Types, 2016
Table 2.6 Clinical Trial Phases, 2016
Table 3.1 The Global Translational Regenerative Medicine Market: Revenue ($m) and Market Shares (%) by Sector, 2016 and 2017
Table 3.2 The Global Translational Regenerative Medicine Market: Market Forecast ($m, AGR% and CAGR%) by Sector, 2016-2021
Table 3.3 The Global Translational Regenerative Medicine Market: Market Forecast ($m, AGR% and CAGR%) by Sector, 2022-2027
Table 3.4 The Global Translational Regenerative Medicine Market Forecast: CAGR (%) by Sector, 2016-2021, 2022-2027 and 2016-2027
Table 3.5 The Global Translational Regenerative Medicine Market: Revenue ($m) by Sector, 2016, 2021 and 2027
Table 3.6 The Global Translational Regenerative Medicine Market: Market Share (%) by Sector, 2016, 2021 and 2027
Table 4.1 Selected Stem Cell Products Currently Available On the Market, 2016
Table 4.2 Stages of Osteogenesis, 2016
Table 4.3 Global Stem Cell Therapies Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 4.4 Global Stem Cell Therapies Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 4.5 Osteocel Plus Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2027
Table 4.6 Osteocel Plus Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2027
Table 4.7 Trinity ELITE Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 4.8 Trinity ELITE Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 4.9 TEMCELL / Prochymal Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 4.10 TEMCELL / Prochymal Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 4.11 Stem Cell Therapy Pipeline: Therapies in Development, Clinical Trials
Table 4.12 Stem Cell Therapy Pipeline: Therapies in Late-Stage Clinical Trials, 2015
Table 5.1 Selected Tissue Engineering Products Currently Available on the Market, 2015
Table 5.2 Global Tissue Engineering Therapies Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 5.3 Global Tissue Engineering Therapies Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 5.4 Apligraf Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 5.5 Apligraf Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 5.6 Dermagraft Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 5.7 Dermagraft Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 5.8 Epifix Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 5.9 Epifix Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 5.10 ReCell Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 5.11 ReCell Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 5.12 Tissue Engineering Pipeline: Therapies in Development, Clinical Trials
Table 5.13 Vital Therapies: Extracorporeal Bio-Artificial Liver Therapy Clinical Trials, 2015
Table 6.1 Currently Available Gene Therapy Products, 2015
Table 6.2 Global Gene Therapies Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 6.3 Global Gene Therapies Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 6.4 Neovasculgen Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 6.5 Neovasculgen Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 6.6 Glybera Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 6.7 Glybera Sales Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 6.8 Amgen: Gene Therapy Clinical Trials, 2015
Table 6.9 Talimogene Laherparepvec (IMLYGIC) Sales Forecast ($m, AGR% and CAGR%), 2016-2021
Table 6.10 Talimogene Laherparepvec (IMLYGIC) Sales Forecast ($m, AGR% and CAGR%), 2022-2027
Table 6.11 Gene Therapy Pipeline: Therapies in Development, Clinical Trials
Table 6.12 Gene Therapy Pipeline: Therapies in Late-Stage Clinical Trials, 2015
Table 6.13 Advantegene: Gene Therapy Clinical Trials, 2015
Table 6.14 Spark Therapeutics: Gene Therapy Clinical Trials, 2015
Table 6.15 Recent Developments in Gene Therapy for Use in Diabetes
Table 6.16 Gene Therapy Products in the Development Pipeline for Neurological Diseases, 2015
Table 7.1 The Global Translational Regenerative Medicine Market: Market Size ($m) and Market Share (%) by Region, 2016 and 2017
Table 7.2 Global Translational Regenerative Medicine Market: Market Forecast ($m), AGR (%) and CAGR (%) by Region, 2016-2021
Table 7.3 Global Translational Regenerative Medicine Market: Market Forecast ($m), AGR (%) and CAGR (%) by Region, 2022-2027
Table 7.4 Global Translational Regenerative Medicine Market: CAGR (%) by Region, 2016-2021, 2022-2027, 2016-2027
Table 7.5 Global Translational Regenerative Medicine Market: Market Share (%) by Region, 2016, 2021 and 2027
Table 7.6 US Translational Regenerative Medicine Market Forecast: Revenue ($m), Market Share (%) and CAGR (%), 2016, 2021 and 2027
Table 7.7 US Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 7.8 US Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 7.9 European Translational Regenerative Medicine Market Forecast: Revenue ($m), Market Share (%) and CAGR (%), 2016, 2021 and 2027
Table 7.10 European Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 7.11 European Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 7.12 Asia-Pacific Translational Regenerative Medicine Market Forecast: Revenue ($m), Market Share (%) and CAGR (%), 2016-2027
Table 7.13 Asia-Pacific Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 7.14 Asia-Pacific Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 7.15 Rest of the World Translational Regenerative Medicine Market Forecast: Revenue ($m), Market Share (%) and CAGR (%), 2016-2027
Table 7.16 Rest of the World Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2016-2021
Table 7.17 Rest of the World Translational Regenerative Medicine Market Market Forecast: Revenue ($m), AGR (%) and CAGR (%), 2022-2027
Table 8.1 Alphatec Spine: Historical Sales ($m) and Operating Profit / Loss ($m), 2011-2015
Table 8.2 Alphatec Spine: Regenerative Medicine Clinical Trials, 2015
Table 8.3 Anterogen: Regenerative Medicine Clinical Trials, 2015
Table 8.4 Athersys: Historical Sales ($m) 2011-2015
Table 8.5 Athersys: Historical Expenditure and Losses ($m) 2011-2015
Table 8.6 Athersys: Regenerative Medicine Clinical Trials, 2015
Table 8.7 Avita Medical: Historical Sales ($m, AUD m) and Net Loss ($m, AUD m), 2011-2015
Table 8.8 Avita Medical: Regenerative Medicine Clinical Trials, 2015
Table 8.9 AxoGen: Historical Sales ($m) and Net Loss ($m), 2011-2015
Table 8.10 AxoGen: Regenerative Medicine Clinical Trials, 2015
Table 8.11 Medipost: Historical Sales ($m, mil.KRW), Net Income ($m, mil.KRW) and Revenue Growth (%) 2011-2015
Table 8.12 Medipost: Historical Sales (mil.KRW), Net Income ($m, mil.KRW) and Revenue Growth (%) 2011-2015
Table 8.13 Medipost: Regenerative Medicine Clinical Trials, 2015
Table 8.14 Mesoblast: Historical Sales ($m, AUD m), 2011-2015
Table 8.15 Mesoblast: Regenerative Medicine Clinical Trials, 2015
Table 8.16 NuVasive: Historical Sales ($m) and Net Income (Profits and Losses) ($m), 2011-2015
Table 8.17 NuVasive: Regenerative Medicine Clinical Trials, 2015
Table 8.18 Ocata Therapeutics: Historical Sales ($thousand) and Gross Income ($thousand), 2011-2015
Table 8.19 Ocata Therapeutic: Regenerative Medicine Clinical Trials, 2015
Table 8.20 Organogenesis: Regenerative Medicine Clinical Trials, 2015
Table 8.21 Osiris Therapeutics: Revenue ($m) and Net Income ($m), 2011-2015
Table 8.22 Osiris Therapeutics: Regenerative Medicine Clinical Trials, 2015
Table 8.23 Pharmicell: Historical Sales ($m, mil.KRW) and Net Income ($m, mil.KRW), 2011-2015
Table 8.24 Regenerys: Regenerative Medicine Clinical Trials, 2015
Table 8.25 TiGenix: Historical Sales (€m, $m) and Net Income (€m, $m), 2011-2015
Table 8.26 TiGenix: Regenerative Medicine Clinical Trials, 2015
Table 8.27 UniQure: Regenerative Medicine Clinical Trials, 2015
Table 8.28 Vericel: Historical Sales ($m and AGR%), 2011-2015
Table 8.29 Vericel: Sales by Product ($m) and Revenue Share (%), 2013-2014
Table 8.30 Vericel Corporation: Regenerative Medicine Clinical Trials, 2015
Table 9.1 SWOT Analysis of the Global Translational Regenerative Medicine Market, 2017-2027
Table 10.1 Global Translational Regenerative Medicine: Market Forecast ($m, CAGR%), 2016, 2022, 2027
Table 10.2 Global Translational Regenerative Medicine Market: Revenue ($m) and Market Shares (%) by Sector, 2016
Table 10.3 Global Translational Regenerative Medicine Market: Revenue ($m) and Market Shares (%) by Region, 2016, 2022 and 2027
Table 10.4 Global Translational Regenerative Medicine: Market Forecast ($m) by Sector, 2016, 2022 and 2027
Table 10.5 Global Translational Regenerative Medicine Market: Products In Late Stage Development, 2015
List of Figures
Figure 1.1 Global Translational Regenerative Medicine Market: Submarkets, 2016
Figure 2.1 Brief History of Stem Cell Research, 1900-2016
Figure 2.2 Examples of FDA-Approved Tissue Engineering Products
Figure 2.3 Brief History of Tissue Engineering, 1900-2015
Figure 2.4 Brief History of Gene Therapy, 1970-2015
Figure 3.1 The Global Translational Regenerative Medicine Market: Revenue ($m) by Sector, 2016 and 2017
Figure 3.2 The Gene Therapy Market: Revenue ($m), 2016 and 2017
Figure 3.3 The Global Translational Regenerative Medicine Market Market Forecast: Revenue ($m) and AGR (%),2016-2027
Figure 3.4 The Global Translational Regenerative Medicine Market Forecast: CAGR (%) by Sector, 2016-2021
Figure 3.5 The Global Translational Regenerative Medicine Market Forecast: CAGR (%) by Sector, 2022-2027
Figure 3.6 The Global Translational Regenerative Medicine Market Forecast: CAGR (%) by Sector, 2016-2027
Figure 3.7 The Global Translational Regenerative Medicine Market: Revenue ($m) by Sector, 2016, 2021 and 2027
Figure 3.8 The Global Translational Regenerative Medicine Market: Market Share (%) by Sector, 2016
Figure 3.9 The Global Translational Regenerative Medicine Market: Market Share (%) by Sector, 2021
Figure 3.10 The Global Translational Regenerative Medicine Market: Market Share (%) by Sector, 2027
Figure 4.1 Global Stem Cell Therapies Market Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 4.2 Osteocel Plus Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 4.3 Trinity ELITE Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 4.4 TEMCELL / Prochymal Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 5.1 Global Tissue Engineering Therapies Market Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 5.2 Apligraf Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 5.3 Dermagraft Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 5.4 Epifix Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 5.5 ReCell Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 5.6 Tissue Engineered Therapy Products: Drivers and Restraints, 2017-2027
Figure 6.1 Global Gene Therapies Market Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 6.2 Neovasculgen Sales Forecast: Revenue ($m) and AGR (%),2016-2027
Figure 6.3 Glybera Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 6.4 Talimogene Laherparepvec (IMLYGIC) Sales Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 6.5 Gene Therapy Products: Market Drivers and Restraints, 2017-2027
Figure 7.1 The Global Translational Regenerative Medicine Market: Market Size ($m) by Region, 2016 and 2017
Figure 7.2 Asia-Pacific, Europe, US, and ‘Rest of the World’ Translational Regenerative Medicine Market: Market Forecast ($m), 2016-2027
Figure 7.3 Global Translational Regenerative Medicine Market: CAGR (%) by Region, 2016-2021
Figure 7.4 Global Translational Regenerative Medicine Market: CAGR (%) by Region, 2022-2027
Figure 7.5 Global Translational Regenerative Medicine Market: CAGR (%) by Region, 2016-2027
Figure 7.6 Global Translational Regenerative Medicine Market: Market Share (%) by Region, 2016
Figure 7.7 Global Translational Regenerative Medicine Market: Market Share (%) by Region, 2021
Figure 7.8 Global Translational Regenerative Medicine Market: Market Share (%) by Region, 2027
Figure 7.9 US Translational Regenerative Medicine: Market Drivers and Restraints, 2017-2027
Figure 7.10 US Translational Regenerative Medicine Market Market Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 7.11 European Translational Regenerative Medicine: Market Drivers and Restraints, 2017-2027
Figure 7.12 European Translational Regenerative Medicine Market Market Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 7.13 Asia-Pacific Translational Regenerative Medicine: Market Drivers and Restraints, 2017-2027
Figure 7.14 Asia-Pacific Translational Regenerative Medicine Market Market Forecast: Revenue ($m) and AGR (%), ss2016-2027
Figure 7.15 Rest of the World Translational Regenerative Medicine Market Market Forecast: Revenue ($m) and AGR (%), 2016-2027
Figure 8.1 Alphatec Spine: Historical Sales ($m) and Operating Loss ($m), 2011-2015
Figure 8.2 Athersys: Historical Sales ($m) 2011-2015
Figure 8.3 Athersys: Historical Revenue, Expenditure and Losses ($m) 2011-2015
Figure 8.4 Avita Medical: Historical Sales ($m, AUD m) and Net Loss ($m), 2011-2015
Figure 8.5 AxoGen: Historical Sales ($m) and Net Loss ($m), 2011-2015
Figure 8.6 Medipost: Historical Sales ($m, mil.KRW) and Net Income ($m, mil.KRW), 2010-2014
Figure 8.7 Medipost: Revenue Share by Business Area (%), 2013
Figure 8.8 Medipost: Revenue Share by Business Area (%), 2014
Figure 8.9 Medipost: Revenue Share by Business Area (%), 2015
Figure 8.10 Mesoblast: Historical Sales (AUD m), 2011-2015
Figure 8.11 NuVasive: Historical Sales and Net Income (Profits and Losses) ($m), 2011-2015
Figure 8.12 Ocata Therapeutics: Historical Sales ($m) and Gross Income ($thousand), 2011-2015
Figure 8.13 Osiris Therapeutics: Revenue ($m) and Net Income ($m), 2011-2015
Figure 8.14 Pharmicell: Historical Sales (mil.KRW) and Net Income (mil.KRW), 2011-2015
Figure 8.15 TiGenix: Historical Sales ($m) and Net Income ($m), 2011-2015
Figure 8.16 Vericel: Historical Sales ($m), 2011-2015 (Limited Scale)
Figure 8.17 Vericel: Revenue Contribution by Product (%) 2014
Figure 9.1 Porter’s Five Force Analysis of the Translational Regenerative Medicine Market, 2016
Figure 10.1 Global Translational Regenerative Medicine: Market Forecast ($m), 2016, 2022 and 2027
Figure 10.2 Global Translational Regenerative Medicine Market: Market Share (%) by Sector, 2016
Figure 10.3 Global Translational Regenerative Medicine: Market Forecast ($m) by Sector, 2016-2027
Abeona Therapeutics Inc.
Advanced BioHealing
Advanced Tissue Sciences
Advantagene
Alliqua BioMedical, Inc.
AlloSource
AlphaTec Spine
Amedica
Amgen
Amorcyte
Amorepacific Group
AnGes MG
Angioblast Systems
Anika Therapeutics
Anterogen
Apceth
Arcarios B.V
Ark Therapeutics
Athersys Inc
Avita Medical
Axiogenesis AG
AxoGen
Baxter
Beike Biotechnology
Benda Pharmaceutical
BioCardia, Inc.
BioD
Bioheart
BioMed Realty Trust, Inc
BioSante Pharmaceuticals
BioTime
BioTissue AG
BioVex Inc
Blackstone Medical
Bluebird bio, Inc.
BrainStorm Cell Therapeutics
Caladrius Biosciences
California Stem Cell Inc
Capricor
Cardio3BioSciences
Celgene
Cell Medica
Cell Targeting
CellCo Tec
Cellerant Therapeutics
Cellular Dynamics International, Inc.
Cephalon
Ceregene
CHA Biotech
Chiesi Farmaceutici
Cipla
Co.don AG
Cold Genesys
Cook Biotech Inc
Cytomedix
Cytori Therapeutics, Inc.
Daiichi Sankyo
DePuy Mitek (Johnson & Johnson)
Dimension Therapeutics, Inc.
FibroCell Science
Gamida Cell Ltd
GE Healthcare
Genzyme Corporation (Sanofi)
Histogenics
Homology Medicines, Inc.
Humacyte
Human Stem Cell Institute
Insulete Inc
Integra LifeSciences
Interxon Corporation
Invetech
Irvine Scientific
ISTO Technologies
Janssen Biotech Inc
Japan Tissue Engineering Co
JCR Pharmaceuticals
Johnson & Johnson
Kinetic Concept Inc
Kite Pharma
LecTec Corporation
Lincoln Park Capital
Lonza
Lonza Houston, Inc.
MacroCure
Medipost
Medtronic
Mesoblast
MiMedx Group, Inc.
Mitsubishi Tanabe
Myriad Genetics
Neostem
Neuralstem
Nippon Zoki Pharmaceuticals
NuVasive
Ocata Therapeutics
OncoCyte
Orchard Therapeutics
Organovo
Orphan Biovitrum AB (Sobi)
Orteq Ltd.
Orthofix
Osiris Therapeutics
Oxford BioMedica
Pall Corporation
Parcell Laboratories
Pfizer, Inc.
Pharmicell
Promethera Biosciences SA
Regenerys
Regeneus
Reliance Life Sciences
ReNeuron
RTI Surgical
Rusnano Corporation
Sangamo Biosciences
Sanofi
Semma Therapeutics
Servier
Shanghai Sunway Biotech
Shenzhen Sibiono GeneTech
Shire
Singapore General Hospital
Skye Orthobiologics
Smith & Nephewbv
Sobi Partners
Spark Therapeutics
StemCells, Inc.
Stempeutics Research
Stratatech Corporation
Takeda Pharmaceuticals
TCA Cellular Therapy
Tengion Inc
Teva Pharmaceuticals
TiGenix
TissueGene, Inc.
U.S. Stem Cell Inc.
UniQure
Vericel Corporation
Viacyte Inc
Vital Therapies
WKD Holding Oy
Xcellerex
Xenetic Biosciences
Zimmer
List of Organisations Mentioned in the Report
Arthritis Research UK
Associazione Infermieristica per lo Studio delle Lesioni Cutanee (AISLeC) [China]
Australian Regenerative Medicine Institute
Australian Sports Anti-Doping Authority (ASADA)
Biomedical Advanced Research and Development Authority (BARDA)
British Heart Foundation [UK]
California Institute of Regenerative Medicine (CIRM)
Cambridge Stem Cell Biology Institute [UK]
Case Western Reserve University
Catalan Institution for Research and Advanced Studies
Center for Biologics Evaluation and Research (CBER) [US]
CHA General Hospital [Korea]
Cryocenter Saint Petersburg
Drugs Controller General of India (DCGI)
European Group for Blood and Marrow Transplantation (EBMT)
European Medicines Agency
Food and Drugs Agency (FDA) [US]
Haute Autorité de santé [France]
Heriot-Watt University
Human Fertilisation and Embryology Authority (HFEA)
Institute of Biomedical Research and Innovation Hospital [Japan]
International Society for Stem Cell Research (ISSCR)
Karolinska Institute [Sweden]
Massachusetts General Hospital (MGH)
Mayo Clinic [US]
Medical Research Council [UK]
MiMedx
Ministry of Food and Drug Safety, MFDS) [Korea]
Ministry of Health, Labour and Welfare (MHLW) [Japan]
Ministry of Science and Technology [China]
Moorfields Eye Hospital
National Tissue Engineering Center (NTEC) [China]
New York Blood Center
Riken Center for Developmental Biology
RUSH University Medical Center [US]
Russian Ministry of Healthcare and Social Development
Scottish Centre for Regenerative Medicine
St. Jude’s Children Research Hospital
State Food and Drug Administration (SFDA) [China]
SUNY Upstate Medical University
The Genetico Center [Russia]
The StemGen Organisation
Therapeutics Goods Administration (TGA) [Australia]
UH San Diego Sanford Stem Cell Clinical Center
UK Medicines and Healthcare Products Regulatory Agency (MHRA)
Universitat Autònoma de Barcelona [Spain]
University College London
University of Edinburgh MRC Centre for Regenerative Medicine [UK]
University of Massachusetts (UMass) Memorial Hospital
University of Modena Centre for Regenerative Medicine [Italy]
University of Wisconsin
US National Institute of Health
Wake Forest Institute
Wellcome Trust
World Health Organization
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American Association of Colleges of Pharmacy
American College of Clinical Pharmacy
American Pharmacists Association
American Society for Pharmacy Law
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American Society of Health-System Pharmacists
Association of Special Pharmaceutical Manufacturers
Australian College of Pharmacy
Biotechnology Industry Organization
Canadian Pharmacists Association
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Chinese Pharmaceutical Association
College of Psychiatric and Neurologic Pharmacists
Danish Association of Pharmaconomists
European Association of Employed Community Pharmacists in Europe
European Medicines Agency
Federal Drugs Agency
General Medical Council
Head of Medicines Agency
International Federation of Pharmaceutical Manufacturers & Associations
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International Pharmaceutical Students’ Federation
Medicines and Healthcare Products Regulatory Agency
National Pharmacy Association
Norwegian Pharmacy Association
Ontario Pharmacists Association
Pakistan Pharmacists Association
Pharmaceutical Association of Mauritius
Pharmaceutical Group of the European Union
Pharmaceutical Society of Australia
Pharmaceutical Society of Ireland
Pharmaceutical Society Of New Zealand
Pharmaceutical Society of Northern Ireland
Professional Compounding Centers of America
Royal Pharmaceutical Society
The American Association of Pharmaceutical Scientists
The BioIndustry Association
The Controlled Release Society
The European Federation of Pharmaceutical Industries and Associations
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