Industries > Pharma > Global Next-Generation Antibody Therapies Market Forecast 2017-2027
Global Next-Generation Antibody Therapies Market Forecast 2017-2027
Antibody-Drug Conjugates (ADC), Biosimilar Antibodies, Engineered Antibodies, Bispecific Antibodies, Antibody Fragments and Antibody-Like Proteins (ALPs)
The global next-generation antibody therapies market is expected to grow at a CAGR of 35.9% in the first half of the forecast period. The market is expected to grow at a CAGR of 22.4% from 2016-2027. The market is estimated at $3.1bn in 2016 and $14.1bn in 2021.
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Report Scope
• Global Next-Generation Antibody Therapies Market forecasts from 2017-2027
• Along with revenue prediction for the overall world market for next-generation antibody therapies, our investigation shows forecasts to 2027 for the following five submarkets:
– Antibody-drug conjugates (ADCs)
– Engineered antibodies
– Bispecific antibodies
– Antibody fragments and antibody-like proteins (ALPs)
– Biosimilar antibody therapies
• How will leading next-generation antibody therapies perform to 2027 at world level? Our study forecasts individual revenues of seven products:
– Adcetris
– Kadcyla
– Gazyva/Gazyvaro
– Poteligeo
– Removab
– Blincyto
– Kalbitor
• Our analyses show individual revenue forecasts to 2027 for these regional markets:
– US
– EU5 group
– Asia-Pacific region
– Latin America
– Rest of the World
• This report discusses issues affecting the next-generation antibody therapies market:
– R&D for next generation antibodies – explore technologies and potentials
– Challenges with current monoclonal antibody (mAb) therapies
– Big pharma companies investing in next-generation antibody research and development
– Biosimilars and their effects on the next-generation antibody therapies market
• Our study discusses strengths, weaknesses, opportunities and threats as well as social, technological, economic and political factors that affect the next-generation antibody therapies market
Visiongain’s study is intended for anyone requiring commercial analyses for the next-generation antibody therapies market. You find data, trends and predictions.
Buy our report today Global Next-Generation Antibody Therapies Market Forecast 2017-2027: Antibody-Drug Conjugates (ADC), Biosimilar Antibodies, Engineered Antibodies, Bispecific Antibodies, Antibody Fragments and Antibody-Like Proteins (ALPs).
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1. Report Overview
1.1 Next-Generation Antibody Therapies Overview
1.2 Global Next-Generation Antibody Therapies Market Segmentation
1.3 Why you Should Read this Report
1.4 How this Report Delivers
1.5 Main Questions Answered by This Analytical Study
1.6 Who is This Report For?
1.7 Methodology
1.8 Frequently Asked Questions (FAQ)
1.9 Associated Reports
1.10 About Visiongain
2. Introduction to Next-Generation Antibody Therapies
2.1 Antibodies: An Overview
2.1.1 Monoclonal versus Polyclonal Antibodies
2.1.2 A Brief History of Antibody Drug Development
2.1.3 The Antibody Manufacturing Process
2.1.4 Trends in Antibody Development
2.2 Defining Next-Generation Antibodies
2.3 Classification of Next-Generation Antibody Therapies
2.4 The Need for Next-Generation Technologies
2.5 Development Trends for Next-Generation Antibodies
2.6 Scope of this Report
2.7 Phases of Clinical Trials
3. Next-Generation Antibody Therapies: World Market 2016-2027
3.1 The World Next-Generation Antibody Therapies Market Overview and Segmentation, 2016
3.2 Leading Next-Generation Antibody Therapies
3.3 World Next-Generation Antibody Therapies Market: Sales Forecast 2016-2027
3.4 How Will Segmental Market Shares Change to 2027?
3.5 World Next-Generation Antibody Therapies Market: Drivers and Restraints 2016-2027
4. Leading Regional Markets 2016-2027
4.1 Regional Breakdown of the World Next-Generation Antibody Therapies Market, 2016
4.2 World Next-Generation Antibody Therapies Market: Regional Forecast 2016-2027
4.3 How Will Regional Market Shares Change to 2027?
4.4 US Next-Generation Antibody Therapies Market 2016-2027
4.5 EU5 Next-Generation Antibody Therapies Market 2016-2027
4.6 Asia-Pacific Next-Generation Antibody Therapies Market 2016-2027
4.7 Latin American Next-Generation Antibody Therapies Market 2016-2027
4.8 The Next-Generation Antibody Therapies Market in the Rest of the World 2016-2027
5. Antibody-Drug Conjugates: Market Forecast and Pipeline 2016-2027
5.1 Market Overview, 2017
5.2 Leading ADCs in 2017
5.3 Antibody-Drug Conjugates: Market Forecast 2016-2027
5.4 The Antibody-Drug Conjugates Market: Drivers and Restraints 2016-2027
5.4.1 Novel Approaches Will Drive ADCs Market Growth
5.4.2 Competition for Leading Drugs Will Restrain Growth
5.4.3 Manufacturing ADCs Forms a Challenge
5.5 Adcetris (brentuximab vedotin, Seattle Genetics / Takeda)
5.5.1 Adcetris: Sales 2011-2016
5.5.2 Adcetris Results in AETHERA Trial and Approval for in HL following Stem Cell Transplantation
5.5.3 Expanding Adcetris Indications for Future Revenue Growth
5.5.4 Adcetris Sales Forecast 2016-2027
5.6 Kadcyla (trastuzumab emtansine, Roche)
5.6.1 Mixed Results from Different Clinical Trials
5.6.2 NICE Rejects Kadcyla on Cost Grounds, but it Just Manages to Hold on in the Cancer Drugs Fund List
5.6.3 Kadcyla Sales Forecast 2016-2027
5.7 Mylotarg (gemtuzumab ozogamicin, Pfizer)
5.7.1 Mylotarg to be Relaunched?
5.8 Antibody-Drug Conjugate Platforms
5.8.1 Limited Market Opportunity for Radioconjugation
5.8.2 Seattle Genetics’ Platform Accounted for Over 40% of the Pipeline in 2016
5.8.3 ImmunoGen: TAP Technology
5.8.4 Immunomedics: Lower Potency Cytotoxics for Extended Use
5.8.5 Preclinical Platforms for ADC Development
5.9 ADCs Have Attracted High-Value Deals and will Continue to do so
5.10 Antibody-Drug Conjugates: Pipeline Analysis 2016-2027
5.10.1 The Longest Pipeline in the Next-Generation Antibodies Market
5.10.2 Cancer Is the Only Target for Current Clinical-Stage ADCs
5.11 Antibody-Drug Conjugates: Phase 3 Pipeline
5.11.1 CMC544 (inotuzumab ozogamicin, Pfizer)
5.11.2 Roche Attempting to Expand Kadcyla Indications and also Possesses some Unique ADCs in the Pipeline
5.12 Antibody-Drug Conjugates: Phase 2 Pipeline
5.12.1 ABT-414 (anti-EGFR, AbbVie/Seattle Genetics)
5.12.2 BT-062 (indatuximab ravtansine; anti-CD138, Biotest)
5.12.3 CDX-011 (glembatumumab vedotin; anti-glycoprotein NMB, Celldex Therapeutics/Seattle Genetics)
5.12.4 Immunomedics’ IMMU-130 (labetuzumab-SN-38; anti-CEA/CD66e) and IMMU-132 (anti-TROP-2)
5.12.5 MLN0264 (anti-GCC, Millennium Pharmaceuticals/Seattle Genetics)
5.12.6 MM-302 (anti-HER2, Merrimack Pharmaceuticals)
5.12.7 PSMA ADC (anti-PSMA, Progenics Pharmaceuticals/Seattle Genetics)
5.12.8 SAR3419 (coltuximab ravtansine) (anti-CD19, Sanofi)
5.12.9 Seattle Genetics’ Phase 1 and Phase 2 ADCs
5.13 Antibody-Drug Conjugates: Phase 1 Pipeline
5.14 Antibody-Drug Conjugates: Preclinical Pipeline
5.15 Future Developments in ADC Technology
5.15.1 Site-Specific Linkage for Improved Safety Profiles
6. Engineered Antibodies: Market Forecast and Pipeline 2016-2027
6.1 Defining an ‘Engineered Antibody’
6.2 Market Overview 2017, and the Leading Engineered Antibodies
6.3 Leading Engineered Antibodies: Market Forecast 2016-2027
6.4 The Engineered Antibodies Market: Drivers and Restraints 2016-2027
6.5 Poteligeo (mogamulizumab, Kyowa Hakko Kirin)
6.5.1 Poteligeo Sales Forecast 2016-2027
6.6 Gazyva / Gazyvaro (obinutuzumab, Roche)
6.6.1 Gazyva as a Challenger in the anti-CD20 Market
6.6.2 Competition beyond Rituxan and Biosimilars
6.6.3 Gazyva Receives Second Approval
6.6.4 Gazyva Sales Forecast 2016-2027
6.7 Engineered Antibodies Platforms
6.7.1 Roche Glycart: GlucoMAb - Glycosylation for Improved ADCC
6.7.2 Kyowa Hakko Kirin: Potelligent – Enhancing ADCC
6.7.3 Glycotope: GlycoExpress
6.7.4 MacroGenics: Fc Optimization
6.7.5 Xencor: XmAb – Modifying Amino Acids in the Fc Domain
6.7.6 Other Platforms for Increased Potency
6.8 Engineered Antibodies: Pipeline Analysis 2016-2027
6.9 Engineered Antibodies: Phase 3 Pipeline
6.9.1 Benralizumab (MedImmune / Kyowa Hakko Kirin)
6.9.2 Elotuzumab (anti-SLAMF7, Bristol-Myers Squibb/AbbVie)
6.9.3 MEDI4736 (anti-PDL1, AstraZeneca)
6.9.4 RG7446/MPDL3280A (anti-PDL1, Roche)
6.9.5 Ublituximab (anti-CD20, TG Therapeutics)
6.10 Engineered Antibodies: Phase 2 Pipeline
6.10.1 Glycotope’s CetuGEX (anti-EGFR), PankoMab-GEX (anti-TA-MUC1) and TrasGEX (anti-HER2)
6.10.2 Margetuximab (anti-HER2, MacroGenics)
6.10.3 MEDI-551 (anti-CD19, AstraZeneca)
6.10.4 MOR-208 (XmAb5574) (anti-CD19, MorphoSys/Xencor)
6.10.5 Teplizumab (anti-CD3, MacroGenics)
6.10.6 BIW-8962 (anti-GM2, Kyowa Hakko Kirin)
6.10.7 XmAb5871 (anti-CD19, Xencor)
6.11 Engineered Antibodies: Phase 1 Pipeline
7. Bispecific Antibodies: Market Forecast and Pipeline 2016-2027
7.1 Bispecific Antibodies: Market Overview, 2017
7.2 Bispecific Antibodies: Market Forecast 2016-2027
7.3 The Bispecific Antibodies Market: Drivers and Restraints 2016-2027
7.4 Removab (catumaxomab, Neopharm)
7.4.1 Removab: Sales Forecast 2016-2027
7.5 Blincyto (blinatumomab, Amgen)
7.5.1 Amgen Files a Supplemental Biologics License Application, and the EU approves Blincyto
7.5.2 Blincyto: Sales Forecast 2016-2027
7.6 Bispecific Antibodies Platforms
7.6.1 BiTE Platform: The Current Market Leader
7.6.2 MacroGenics’ DART Platform Holds Promise
7.6.3 TriomAbs (TRION Pharma): Limited Market Impact 2016-2027
7.6.4 Other Bispecific Antibody Platforms
7.7 Bispecific Antibodies: Pipeline Analysis 2016-2027
7.7.1 Bispecific Antibodies: Phase 2 and Phase 3 Pipeline
7.7.2 ABT-122 (anti-TNF and IL-17A) and ABT-981 (anti-IL-1α and IL-1β, AbbVie)
7.7.3 AFM13 (anti-CD30 and CD16A, Affimed Therapeutics)
7.7.4 MM-111 (anti-ErbB2 and ErbB3, Merrimack Pharmaceuticals)
7.7.5 MM-141 (anti-IGF-1R and ErbB3, Merrimack Pharmaceuticals)
7.7.6 SAR156597 (anti-IL-4 and IL-13, Sanofi)
7.7.7 Vanucizumab (RG7221; anti-Ang2 and VEGF-A, Roche)
7.8 Bispecific Antibodies: Phase 1, Phase 1/2 and Preclinical Pipeline
8. Antibody Fragments and Antibody-Like Proteins (ALPs): Market Forecast and Pipeline 2016-2027
8.1 Antibody Fragments and ALPs: Market Overview, 2017
8.2 Antibody Fragments and ALPs: Market Forecast 2016-2027
8.3 The Antibody Fragments and ALPs Market: Drivers and Restraints 2016-2027
8.4 Kalbitor (ecallantide, Shire): Shire Completes Acquisition of Dyax and adds Kalbitor to Portfolio
8.4.1 Kalbitor: Sales Forecast 2016-2027
8.5 Antibody Fragments and ALPs Platforms
8.5.1 Single-chain Variable Fragment Platforms
8.5.2 Non-Antibody Protein Scaffolds: Antibody-Like Proteins
8.5.3 Which Platform Will Lead the Market 2016-2027?
8.6 Antibody Fragments and ALPs: Pipeline Analysis 2016-2027
8.6.1 Ablynx Leads the Pipeline with Six Clinical Projects
8.7 Antibody Fragments and ALPs: Phase 3 Pipeline
8.7.1 Caplacizumab (anti-vWF, Ablynx)
8.7.2 Abicipar (anti-VEGF, Allergan/Molecular Partners)
8.8 Antibody Fragments and ALPs: Phase 2 Pipeline
8.8.1 ALX-0061 (anti-IL-6R, Ablynx/AbbVie)
8.8.2 Ozoralizumab (anti-TNFα, Ablynx )
8.8.3 DLX105 (anti-TNF-α, Delenex Therapeutics)
8.8.4 ESBA1008 (anti-VEGF, Novartis)
8.9 Antibody Fragments and ALPs: Phase 1 Pipeline
8.9.1 ALX-0761 (anti-IL-17A and IL-17F, Ablynx/Merck Serono)
8.9.2 ALX-0171 (anti-respiratory syncytial virus)
8.9.3 ALX-0141 (anti-RANKL, Ablynx/Eddingpharm)
8.9.4 Other Phase 1 Candidates, and the Preclinical Pipeline
9. Biosimilar Antibodies: Market Forecast 2016-2027
9.1 Biosimilar Antibodies: Market Overview, 2017
9.2 Leading Biosimilar Antibodies in 2016.
9.3 Biosimilar Antibodies: Market Forecast 2016-2027
9.4 The Biosimilar Antibodies Market: Drivers and Restraints 2016-2027
9.4.1 New Launches of Biosimilar mAbs in Developed and Emerging Markets
9.4.2 Rising Incidence of Cancer will Drive Demand
9.4.3 Novel mAb Developers Choosing to Develop Biobetters and Next-Generation Therapies in Face of Biosimilar Competition
9.4.4 Will Biosimilars Challenge Next-Generation Antibodies in this Decade?
10. Qualitative Analysis of the Next-Generation Antibody Therapies Market 2016-2027
10.1 SWOT Analysis of the Next-Generation Antibody Therapies Market
10.1.1 Strengths: The Path Towards Market Acceptance
10.1.2 Weaknesses: Multiple Companies Targeting Similar Indications
10.1.3 Opportunities: Novel Platforms
10.1.4 Threats: Entry of Biosimilars
10.2 STEP Analysis of the Next-Generation Antibody Therapies Market
10.2.1 Social Factors: Rising Demand for Cancer Therapies
10.2.2 Technological Developments Will Drive Pipeline Growth
10.2.3 Economic Pressures
10.2.4 Political and Regulatory Issues
10.3 Key Targets for Next-Generation Antibody Development 2016-2027
10.3.1 Oncology Is the Lead Indication in All Sectors
11. Conclusions
11.1 High Growth Potential in the Next-Generation Antibody Therapies Market in 2016-2027
11.2 Current Status of the Market and Leading Segments
11.3 Leading Next-Generation Antibody Therapies Profiled in this Report
11.4 Leading Regional Markets
11.5 Development of the Market to 2027
11.6 Technology Platforms Will Continue to Attract Big Pharma Interest
11.7 Most Developers Continue to Target Cancer
11.8 Strategies for Growth in 2016-2027
12. Glossary
Some Associated Reports
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List of Tables
Table 1.1 (Sample) World Next-Generation Antibody Therapies Market Forecast: Revenue ($m), AGR (%), CAGR (%) by Segment, 2016-2021
Table 2.1 Monoclonal Antibody Types and Sources, 2017
Table 2.2 The Different Phases of Clinical Trials and What They Assess
Table 3.1 World Next-Generation Antibody Therapies Market: Revenue ($m) and Market Share (%) by Segment, 2016
Table 3.2 World Next-Generation Antibody Therapies Market Forecast: Revenue ($m), AGR (%), CAGR (%) by Segment, 2016-2021
Table 3.3 World Next-Generation Antibody Therapies Market Forecast: Revenue ($m), AGR (%), CAGR (%) by Segment, 2022-2027
Table 3.4 World Next-Generation Antibody Therapies Market: Revenue ($m) and Market Share (%) by Segment, 2027
Table 4.1 World Next-Generation Antibody Therapies Market: Revenues ($m) and Market Shares (%) by Region, 2016
Table 4.2 World Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) by Region, 2016-2021
Table 4.3 World Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) by Region, 2022-2027
Table 4.4 Revenue ($m) and Market Shares (%) of Leading Regional Next-Generation Antibody Therapies Markets, 2027
Table 4.5 US Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2016-2021
Table 4.6 US Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2022-2027
Table 4.7 EU5 Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2016-2021
Table 4.8 EU5 Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2022-2027
Table 4.9 Asia-Pacific Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2016-2021
Table 4.10 Asia-Pacific Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2022-2027
Table 4.11 Latin American Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2016-2021
Table 4.12 Latin American Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2022-2027
Table 4.13 Rest of the World Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2016-2021
Table 4.14 Rest of the World Next-Generation Antibody Therapies Market Forecast: Revenues ($m), AGR (%), CAGR (%), Global Market Share (%) 2022-2027
Table 5.1 ADC Market Forecast: Revenues ($m), AGR (%), CAGR (%) by Drug, 2016-2021
Table 5.2 ADC Market Forecast: Revenues ($m), AGR (%), CAGR (%) by Drug, 2022-2027
Table 5.3 Seattle Genetics: Adcetris Revenue ($m), 2011-2016
Table 5.4 Total Adcetris Revenue (Seattle Genetics and Takeda): Revenue ($m), 2013-2016
Table 5.5 Total Adcetris Revenue Forecast (Seattle Genetics and Takeda): Revenue ($m), AGR (%), CAGR (%), 2016-2021
Table 5.6 Total Adcetris Revenue Forecast (Seattle Genetics and Takeda): Revenue ($m), AGR (%), CAGR (%), 2022-2027
Table 5.7 Kadcyla Revenue Forecast (Roche): Revenue ($m), AGR (%), CAGR (%), 2016-2021
Table 5.8 Kadcyla Revenue Forecast (Roche): Revenue ($m), AGR (%), CAGR (%), 2022-2027
Table 5.9 ADC Pipeline by Platform and Phase, 2016
Table 5.10 Selected Preclinical ADC Development Platforms, 2016
Table 5.11 ADC Pipeline by Indication and Phase, 2016
Table 5.12 ADC Pipeline by Indication and Phase 3, 2016
Table 5.13 Selected Ongoing Clinical Trials for CMC544 (inotuzumab ozogamicin), 2016
Table 5.14 Roche’s Antibody-Drug Conjugates Pipeline, 2016
Table 5.15 Ongoing Clinical Trials for RG7596 (polatuzumab vedotin), 2016
Table 5.16 Antibody-Drug Conjugates: Phase 2 Pipeline, 2016
Table 5.17 Ongoing Clinical Trials for ABT-414, 2016
Table 5.18 Antibody-Drug Conjugates: Phase 1 Pipeline, Table 1, 2015 and 2016
Table 5.19 Antibody-Drug Conjugates: Phase 1 Pipeline, Table 2, 2016
Table 5.20 Antibody-Drug Conjugates: Preclinical Pipeline, 2016
Table 6.1 Engineered Antibodies Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2016-2021
Table 6.2 Engineered Antibodies Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2022-2027
Table 6.3 Total Poteligeo Revenue Forecast (Kyowa Hakko Kirin): Revenue ($m), AGR (%), CAGR (%), 2016-2021
Table 6.4 Total Poteligeo Revenue Forecast (Kyowa Hakko Kirin): Revenue ($m), AGR (%), CAGR (%), 2022-2027
Table 6.5 Total Gazyva Revenue Forecast (Roche): Revenue ($m), AGR (%), CAGR (%), 2016-2021
Table 6.6 Total Gazyva Revenue Forecast (Roche): Revenue ($m), AGR (%), CAGR (%), 2022-2027
Table 6.7 Engineered Antibodies Pipeline by Company and Phase, 2016
Table 6.8 Selected Licensing Agreements for the Potelligent Platform and Cell Lines, 2008-2015
Table 6.9 Engineered Antibodies Pipeline by Indication and Phase, 2016
Table 6.10 Engineered Antibodies: Phase 3 Pipeline, 2016
Table 6.11 Engineered Antibodies: Phase 2 Pipeline, 2016
Table 6.12 Margetuximab Recent and Ongoing Clinical Trials, 2016
Table 6.13 MEDI-551 Recent and Ongoing Clinical Trials, 2016
Table 6.14 Engineered Antibodies: Phase 1 Pipeline, 2016
Table 7.1 Bispecific Antibodies Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2016-2021
Table 7.2 Bispecific Antibodies Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2022-2027
Table 7.3 Removab (Neopharm) Revenue Forecast: Revenue ($m), AGR (%), CAGR (%), 2016-2021
Table 7.4 Removab (Neopharm) Revenue Forecast: Revenue ($m), AGR (%), CAGR (%), 2021-2026
Table 7.5 Blincyto Revenue Forecast (Amgen): Revenue ($m), AGR (%), CAGR (%), 2016-2021
Table 7.6 Blincyto Revenue Forecast (Amgen): Revenue ($m), AGR (%), CAGR (%), 2022-2027
Table 7.7 Bispecific Antibodies Pipeline by Company and Phase, 2016
Table 7.8 Selected Preclinical Bispecific Antibody Platforms, 2016
Table 7.9 Bispecific Antibodies Pipeline by Indication and Phase, 2016
Table 7.10 Bispecific Antibodies Pipeline by Indication and Phase, 2016
Table 7.11 Bispecific Antibodies: Phase 1/2 Pipeline, 2016, Table 1
Table 7.12 Bispecific Antibodies: Phase 1 Pipeline, 2016, Table 2
Table 7.13 Bispecific Antibodies: Preclinical Pipeline, 2016
Table 8.1 Antibody Fragments and ALPs Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2016-2021
Table 8.2 Antibody Fragments and ALPs Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2022-2027
Table 8.3 Kalbitor Revenue Forecast (Shire): Revenue ($m), AGR (%), CAGR (%), 2016-2021
Table 8.4 Kalbitor Revenue Forecast (Shire): Revenue ($m), AGR (%), CAGR (%), 2022-2027
Table 8.5 Ablynx: Selected Big Pharma Collaboration Agreements, 2012-2015
Table 8.6 Antibody Fragments and ALPs Pipeline by Company and Phase, 2016
Table 8.7 Antibody Fragments and ALPs Pipeline by Indication and Phase, 2016
Table 8.8 Antibody Fragments and ALPs: Phase 1 Pipeline, 2016
Table 8.9 Antibody Fragments and ALPs: Preclinical Pipeline, 2016
Table 9.1 Top Ten Best-Selling Drugs of 2014 (Within the Overall Pharmaceutical Market): Revenues ($bn), Market Shares (%)
Table 9.2 Biosimilar Monoclonal Antibodies Market and Submarkets Forecast: Revenue ($bn), AGR (%), CAGR (%), 2016-2021
Table 9.3 Biosimilar Monoclonal Antibodies Market and Submarkets Forecast: Revenue ($bn), AGR (%), CAGR (%), 2022-2027
Table 9.4 Biosimilar Monoclonal Antibodies Market Forecast: Revenue ($bn), AGR (%), CAGR (%), 2016-2021
Table 9.5 Biosimilar Monoclonal Antibodies Market Forecast: Revenue ($bn), AGR (%), CAGR (%), 2022-2027
Table 9.6 Patent Status of Five Leading mAbs, 2016
Table 10.1 Next-Generation Antibody Therapies Market: STEP Analysis, 2016-2027
Table 10.2 Selected CMOs Investing in Next-Generation Antibody Technologies, 2005-2015
Table 10.3 HER2 and HER3-Targeting Next-Generation Antibodies: Pipeline, 2016
Table 10.4 CD19 and CD20-Targeting Next-Generation Antibodies: Pipeline, 2016
List of Figures
Figure 1.1 Global Next-Generation Antibody Therapies Market Segmentation Overview, 2017
Figure 3.1 World Next-Generation Antibody Therapies Market: Revenue ($m) by Segment, 2016
Figure 3.2 World Next-Generation Antibody Therapies Market Forecast: Revenue ($m), AGR (%) by Segment, 2016-2027
Figure 3.3 World Next-Generation Antibody Therapies Market: Revenue ($m) by Segment, 2027
Figure 3.4 World Next-Generation Antibody Therapies Market: Drivers and Restraints, 2016-2027
Figure 4.1 World Next-Generation Antibody Therapies Market: Revenues ($m) by Region, 2016
Figure 4.2 World Next-Generation Antibody Therapies Market Forecast: Revenues ($m) by Region, 2016-2027
Figure 4.3 World Next-Generation Antibody Therapies Market: Revenue ($m) by Region, 2027
Figure 4.4 US Next-Generation Antibody Therapies Market Forecast: Revenues ($m) and AGR (%), 2016-2027
Figure 4.5 EU5 Next-Generation Antibody Therapies Market Forecast: Revenues ($m) and AGR (%), 2016-2027
Figure 4.6 Asia-Pacific Next-Generation Antibody Therapies Market Forecast: Revenues ($m) and AGR (%), 2016-2027
Figure 4.7 Latin American Next-Generation Antibody Therapies Market Forecast: Revenues ($m) and AGR (%), 2016-2027
Figure 4.8 Rest of the World Next-Generation Antibody Therapies Market Forecast: Revenues ($m) and AGR (%), 2016-2027
Figure 5.1 ADC Market Forecast: Revenues ($m) and AGR (%), 2016-2027
Figure 5.2 ADC Market: Drivers and Restraints, 2016-2027
Figure 5.3 Seattle Genetics: Adcetris Revenue ($m) and AGR (%), 2011-2016
Figure 5.4 Total Adcetris Revenue (Seattle Genetics and Takeda): Revenue ($m) and AGR (%), 2013-2016
Figure 5.5 Total Adcetris Revenue Forecast (Seattle Genetics and Takeda): Revenue ($m) and AGR (%), 2016-2027
Figure 5.6 Kadcyla Revenue Forecast (Roche): Revenue ($m), 2016-2027
Figure 5.7 ADC Pipeline by Platform, 2016
Figure 5.8 ADC Pipeline by Phase, 2016
Figure 5.9 ADC Pipeline by Indication, 2016
Figure 6.1 Engineered Antibodies Market Forecast: Revenues ($m), 2016-2027
Figure 6.2 Engineered Antibodies Market: Drivers and Restraints, 2016-2027
Figure 6.3 Total Poteligeo Revenue Forecast (Kyowa Hakko Kirin): Revenue ($m), 2016-2027
Figure 6.4 Total Gazyva Revenue Forecast (Roche): Revenue ($m), 2016-2027
Figure 6.5 Engineered Antibodies Pipeline by Company, 2016
Figure 6.6 Engineered Antibodies Pipeline by Indication, 2016
Figure 6.7 Engineered Antibodies Pipeline by Phase, 2016
Figure 7.1 Bispecific Antibodies Market: Drivers and Restraints, 2016-2027
Figure 7.2 Bispecific Antibodies Market Forecast: Revenue ($m), 2016-2027
Figure 7.3 Removab (Neopharm) Revenue Forecast: Revenue ($m), 2016-2027
Figure 7.4 Blincyto Revenue Forecast (Amgen): Revenue ($m) and AGR (%), 2016-2027
Figure 7.5 Bispecific Antibodies Pipeline by Company, 2016
Figure 7.6 Bispecific Antibodies Pipeline by Indication, 2016
Figure 7.7 Bispecific Antibodies Pipeline by Phase, 2016
Figure 8.1 Antibody Fragments and ALPs Market Forecast: Revenues ($m), 2016-2027
Figure 8.2 Antibody Fragments and ALPs Market: Drivers and Restraints, 2016-2027
Figure 8.3 Kalbitor Revenue Forecast (Shire): Revenue ($m) and AGR (%), 2016-2027
Figure 8.4 Antibody Fragments and ALPs Pipeline by Company, 2016
Figure 8.5 Antibody Fragments and ALPs Pipeline by Indication, 2016
Figure 8.6 Antibody Fragments and ALPs Pipeline by Phase, 2016
Figure 9.1 Biosimilar Monoclonal Antibody Market Forecast, Split by Product: Revenue ($bn), 2016-2027
Figure 9.2 Biosimilar Monoclonal Antibodies Market Forecast: Revenue ($bn) and AGR(%), 2016-2027
Figure 10.1 Next-Generation Antibody Therapies Market: Strengths and Weaknesses, 2016-2027
Figure 10.2 Next-Generation Antibody Therapies Market: Opportunities and Threats, 2016-2026
AbbVie
Ablynx
AdAlta
ADC Therapeutics
Affimed Therapeutics
Agensys
Alcon
Alexion
Allergan
Ambrx
Amgen
arGEN-X
Astellas Pharma
AstraZeneca
Bayer
Biogen Idec
BioNet Ventures
Biotest
BioWa
Boehringer Ingelheim
Bristol-Myers Squibb
Cancer Drugs Fund
Catalent Pharma Solutions
Celgene
Celldex Therapeutics
Cephalon
Cilag GmbH International
Coldstream Laboratories
Concortis Biosystems
Corixa
Covagen
Crescendo Biologics
CSL Behring
CVie Therapeutics
Daiichi Sankyo
Defiante Farmaceutica
Delenex Therapeutics
Domantis
Dutalys
Dyax
Eddingpharm
Eisai
Eli Lilly
ESBATech
FDA
Five Prime Therapeutics
Fresenius Biotech
F-Star
Fujifilm
Genentech
Genmab
Gilead Sciences
Glenmark
Glycotope
Goodwin Biotechnology
GSK
Igenica
Immunocore
ImmunoGen
Immunomedics
Janssen Biotech
Kalobios
Karolinska Institute
Kyowa Hakko Kirin
Kyowa Medex
LINDIS Biotech
Lonza
MacroGenics
MedImmune
Merck
Merrimack Pharmaceuticals
Mersana Therapeutics
Merus
Micromet
Millennium Pharmaceuticals
Molecular Partners
MorphoSys
MultiCell Immunotherapeutics (MCIT)
National Institute of Diabetes and Digestive and Kidney Diseases
Neopharm
Neovii Biotech
NHS
NICE
Novartis
Novartis Institutes for BioMedical Research (NIBR)
NovImmune
Oxford BioTherapeutics
Oxis
Pfizer
Pharmacyclics
Piramal Healthcare
Pieris
Piramal Enterprises
PolyTherics
Progenics
ProStrakan
Redwood BioScience
Roche
Salix
Sanofi
Scil Proteins
Seattle Genetics
Servier
Shinogi
Shire
Sigma-Tau
Sorrento Therapeutics
Spectrum Pharmaceuticals
Spirogen
Stelis Biopharma
Strides Arcolab
Sutro Biopharma
Swedish Orphan Biovitrum (Sobi)
Swiss Federal Institute of Technology
Synthon
Takeda
Talon Therapeutics
Teva
TG Therapeutics
The American Society of Hematology
TRION Pharma
UCB
WHO
Wyeth
Xencor
Zydus Cadila
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American Association of Colleges of Pharmacy
American College of Clinical Pharmacy
American Pharmacists Association
American Society for Pharmacy Law
American Society of Consultant Pharmacists
American Society of Health-System Pharmacists
Association of Special Pharmaceutical Manufacturers
Australian College of Pharmacy
Biotechnology Industry Organization
Canadian Pharmacists Association
Canadian Society of Hospital Pharmacists
Chinese Pharmaceutical Association
College of Psychiatric and Neurologic Pharmacists
Danish Association of Pharmaconomists
European Association of Employed Community Pharmacists in Europe
European Medicines Agency
Federal Drugs Agency
General Medical Council
Head of Medicines Agency
International Federation of Pharmaceutical Manufacturers & Associations
International Pharmaceutical Federation
International Pharmaceutical Students’ Federation
Medicines and Healthcare Products Regulatory Agency
National Pharmacy Association
Norwegian Pharmacy Association
Ontario Pharmacists Association
Pakistan Pharmacists Association
Pharmaceutical Association of Mauritius
Pharmaceutical Group of the European Union
Pharmaceutical Society of Australia
Pharmaceutical Society of Ireland
Pharmaceutical Society Of New Zealand
Pharmaceutical Society of Northern Ireland
Professional Compounding Centers of America
Royal Pharmaceutical Society
The American Association of Pharmaceutical Scientists
The BioIndustry Association
The Controlled Release Society
The European Federation of Pharmaceutical Industries and Associations
The European Personalised Medicine Association
The Institute of Clinical Research
The International Society for Pharmaceutical Engineering
The Pharmaceutical Association of Israel
The Pharmaceutical Research and Manufacturers of America
The Pharmacy Guild of Australia
The Society of Hospital Pharmacists of Australia
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