07 November 2019
Visiongain has launched a new pharma report “Sarcoma Drugs Market Report ” Prospects by Treatment Type (Chemotherapy, Targeted Therapy, Anti-angiogenesis drugs, Radiation Therapy), and Geography.
Global sarcoma drugs market is projected to grow on account of growing adoption of novel drugs, rising incidences of soft tissue sarcomas, and presence of strong development pipeline among other contributing factors. The global market is projected to grow at a lucrative CAGR of ~9% and anticipated to surpass USD 850 Million by 2020.
Sarcomas are rare connective tissue tumors that affect any part of the body, including bones, nerves, tendons, muscle, and hair. While sarcomas constitute a heterogeneous group of more than 50 distinct histological subtypes, soft tissue sarcomas (STS) account for over 85% of all cases of sarcoma, while malignant bone sarcomas account for close to 15% of all cases. Globally, STS's annual rate of occurrence is 2-3 per 100,000. Risk factors include genetic mutation such as inherited defects in TP53 gene, APC gene, and RB1 gene, compromised lymph system, radiation, and chemical exposure,
In 2017, the U.S. reported over 12,500 fresh diagnoses and 5,000 deaths from STS. There were more than 3,300 new cases of bone sarcomas and 1,650 deaths in 2017. The risk of developing a sarcoma in life is around 0.4%. In the age group of 0-35 years, approximately 45% of bone sarcomas and 20% of STS are diagnosed.
The demand for sarcoma drugs is gaining interest due to growing patient assistance programs, new product launches by large pharmaceutical companies and the rising focus of these companies on R&D, which contributes to the development of new and advanced therapies.
However, over the past 10 years, the price of prescription drugs has increased steadily, sometimes at a double-digit level. This has led to an increase in total spending on health care, making drugs disproportionately inaccessible for those with limited resources.
In 2018 over 45 million Americans did not have health coverage, according to the Kaiser Family Foundation, and millions of people were underinsured, with 8 out of 10 uninsured persons coming from salaried families. 4 out of 10 individuals who are 65 years of age or younger and 1 out of 3 people over the age of 65 had no drug medication coverage among those with health insurance.
The Patient Assistance Programs (PAPs) have emerged to help patients without health insurance and prescription drug coverage to access the treatment they need. Such services are generally provided by pharmaceutical companies that provide prescription drugs free or low-cost to patients suffering from severe illnesses. Most states offer services for prescription assistance that vary from state to state and care for the aged, disabled, or those in financial need. Many services are condition-specific, such as leukemia.
Targeted therapy and chemotherapy regimens are currently the 2 most popular forms of therapeutics in the market for sarcoma drugs. Between the two, due to its higher effectiveness, the targeted therapy is expected to see greater adoption in the near future. These therapies use immune-formulated drugs and antibodies to inhibit the proliferation of dangerous cancer cells while leaving the normal cells undamaged.
In 2018, U.S. dominated the sarcoma drugs market and is anticipated to maintain the leading position over the forecast period. Some of the factors responsible for its dominating position are fresh product releases during the forecast period, increased acceptance of new treatments, and the involvement of key manufacturers in the U.S. EU5 has a major market share and is likely to show substantial growth over the forecast period. It is expected that there will be a greater understanding of tumor microenvironment, further promoting the development of new patient-specific therapies in the coming years.
Some of the major players operating in this industry are Bayer, Bristol-Myers Squibb, Celgene Corporation, Eisai, Eli Lilly and Company, Genentech USA, GlaxoSmithKline, Hoffmann-La Roche Ltd, Johnson & Johnson Services, Inc., Novartis, Pfizer, Inc., and Teva Pharmaceuticals among other prominent players.
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