Respirator disorders affect hundreds of millions of people worldwide, with an estimated 300 million people suffering from asthma and a further 210 million having chronic obstructive pulmonary disease (COPD).
The primary treatment of these diseases is through inhaled medication, and metered dose inhalers (MDIs) are the most widely used delivery system.
MDIs have a number of advantages over alternative systems such as nebulisers oral therapy for respiratory diseases. MDIs provide rapid treatment of respiratory disorders, are easy-to-use and provide excellent reliability and high patient compliance.
A typical MDI system consists of a metal canister, which contains the medication as a pressurised aerosol, with a crimped cap on the mouth of the canister that contains the drug metering valve. The system is enclosed in an actuator through which the patient inhales the drug.
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