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Statins: The World Market, 2009-2024

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Publication date: 03/03/2009
Number of Pages: 144

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The world statins market is changing, with patent expires and maturity of the landmark product Lipitor (atorvastatin). Statins are at the forefront of strategies to combat dyslipidaemia, being pivotal in the prevention of coronary heart disease. Consequently, those drugs are one of the most widely-prescribed and most lucrative sectors of the pharmaceutical industry, with total revenues exceeding $26 billion in 2008. Importantly, the world statins market is poised to undergo a period of rapid and dynamic change, with the generic statin sector growing particularly strongly in the years ahead. When will annual sales of generic statins exceed those of branded statins? Which branded statin will continue to achieve year-on-year sales growth during the coming waves of generic competition? Statins: The World Market, 2009-2024 answers these vital questions – amongst others - and provides the essential information that you need to take advantage of opportunities in the changing statin drugs market from 2009 onwards.

Statins: The World Market, 2009-2024 provides a comprehensive analysis of the world statins market, compiled using a wealth of research tools – including interviews with key opinion-leaders, examination of commercial databases, company reports, policy documents, industry news and filings. This original study provides extensive sales forecasting, market shares present and future, informed opinion, as well as detailed analysis of unmet needs, pipeline developments and commercial opportunities for statin drugs.

Highlights of Statins: The World Market, 2009-2024 include:
• Forecasts to 2024 for the overall world statin market, the generic statin market, the branded statin market and the dyslipidaemia market, including all statin types, the leading statin brands, leading manufacturers, country markets and combination statin drugs
• Interviews with key-opinion leaders in the field
• Examination of strengths, weakness, opportunities and threats facing major stakeholders in the sector – the market drivers and restraints
• Analysis and forecasts for the leading statin markets in the US, Japan and Canada, together with leading European and emerging national markets
• Analysis of the R&D pipeline for new statins, as well as other lipid-lowering drug types.

With full market forecasts for all the major generic statins, this new visiongain report reveals the significant commercial opportunities in new sectors of the statin market. However, significant opportunities exist for original branded products too. With relatively few single statins currently in development, new product developments in statins will mainly focus on statin combination drugs, visiongain predicts. In addition, strong growth in the statins sector will occur in emerging national markets - most notably in China and India - driving global sales. There are vast and expanding existing and potential patient populations for those drugs worldwide.

Importantly, there are opportunities for companies to raise sales by maximising patient compliance and accessing new patient groups. Statins: The World Market, 2009-2024 examines strategies for increasing patient compliance there. The report has detailed interviews with key-opinion leaders in this important field. Full interview transcripts are provided – you will not find this information anywhere else.

Why you should buy this report:
• To receive a comprehensive analysis of the prospects for statins from 2009-2024, including predicted revenues, growth rates, market shares and other key metrics
• To identify key pipeline developments and up-and-coming products, both in the field of statins, and for other lipid-lowering therapies
• To discover the drivers, restraints, competition and opportunities influencing the global statins market –for leading brands, generics and statin combination drugs
• To receive forecasts for leading statin country markets and major emerging markets for statin drugs, including China and India
• To find out where that market sector is heading - both technologically and commercially - from the present onwards.

Statins: The World Market, 2009-2024 is essential reading for everybody involved in the statins market, revealing prospects for both existing competitors and potential market entrants from the present onwards.

Visiongain is a trading partner with the US Federal Government
CCR Ref number: KD4R6

1 Executive Summary

2 Dyslipidaemia and Coronary Heart Disease
2.1 Cholesterol and Triglycerides
2.2 Lipoproteins Transport Cholesterol and Triglycerides
2.3 Dyslipidaemia and Atherosclerosis
2.4 Cholesterol Risk Levels
2.5 The Fredrickson/World Health Organization (WHO) Classification of Dyslipidaemia
2.6 Cardiovascular Disease
2.7 CHD Risk Factors
2.8 Cholesterol Testing
2.9 Primary and Secondary Prevention of Atherosclerosis

3 Statins and Other Lipid-Lowering Drugs
3.1 Statins: Mechanism of Action and Types
3.2 Lovastatin
3.2.1 Lovastatin Indications
3.2.2 Lovastatin Brands and Generic Manufacturers
3.3 Simvastatin
3.3.1 Simvastatin Indications
3.3.2 Simvastatin Brands and Generic Manufacturers
3.4 Pravastatin
3.4.1 Pravastatin Indications
3.4.2 Pravastatin Brands and Generic Manufacturers
3.5 Fluvastatin
3.5.1 Fluvastatin Indications
3.5.2 Fluvastatin Brands and Generic Manufacturers
3.6 Atorvastatin
3.6.1 Atorvastatin Indications
3.6.2 Atorvastatin Brands and Generic Manufacturers
3.7 Rosuvastatin
3.7.1 Rosuvastatin Indications
3.7.2 Rosuvastatin Brands and Generic Manufacturers
3.8 Pitavastatin
3.9 Statin/Other Lipid-Lowering Drug Combinations
3.9.1 Lovastatin/Nicotinic Acid
3.9.2 Simvastatin/Nicotinic Acid
3.9.3 Simvastatin/Ezetimibe
3.9.4 Atorvastatin/Fenofibrate
3.9.5 Atorvastatin/Ezetimibe
3.9.6 Atorvastatin/Ezetimibe/Fenofibrate
3.10 Statin/Other Cardiovascular Drug Combinations
3.10.1 Caduet (Atorvastatin/Amlodipine)
3.10.2 Pravadual (Pravastatin/Aspirin)
3.10.3 Generic Statin/Other Cardiovascular Drugs
3.11 Other Dyslipidaemia Drugs
3.11.1 Anion-Exchange Resins
3.11.2 Ezetimibe
3.11.3 Fibrates
3.11.4 Nicotinic Acid
3.11.5 Omega-3-Acid Ethyl Esters

4 The World Statin Market
4.1 Statins Dominate the Lipid-Lowering Drug Market
4.1.1 The World Lipid-Lowering Drug Market
4.1.2 World Lipid-Lowering Drug Market Forecast, 2009-2024
4.2 The World Statin Market, 2009-2024
4.2.1 The World Statin Market, 2008
4.2.2 Scope for Further Growth: World Statin Market Forecast, 2009-2011
4.2.3 The Impact of Atorvastatin Genericisation on the World Statin Market, 2011-2014
4.2.4 Further Generic Opportunities: World Statin Market Forecast, 2014-2019
4.2.5 What are the Prospects for the World Statin Market from 2019 to 2024?
4.2.6 Statin Type Market Forecast, 2009-2024
4.3 The Branded and Generic Statin Markets
4.3.1 The Branded and Generic Statin Markets, 2008
4.3.2 By 2018 Sales of Generic Statins Will Exceed Branded Revenues
4.4 Atorvastatin
4.4.1 The Atorvastatin Market in 2008
4.4.2 Atorvastatin Market Forecast, 2009-2024
4.4.3 Lipitor Market Forecast, 2009-2011
4.4.4 The Ultimate Patent Cliff: Lipitor Market Forecast, 2011-2014
4.4.5 The Fate of Lipitor: Market Forecast, 2014-2024
4.4.6 Generic Atorvastatin Market Forecast, 2009-2024
4.5 Rosuvastatin
4.5.1 The Rosuvastatin Market in 2008
4.5.2 Rosuvastatin Market Forecast, 2009-2024
4.5.3 Bucking the Trend of Other Branded Statins: Crestor Market Forecast, 2009-2014
4.5.4 What are Crestor’s Prospects During 2014-2024?
4.5.5 Generic Rosuvastatin Market Forecast, 2009-2024
4.6 Simvastatin
4.6.1 The Simvastatin Market in 2008
4.6.2 Simvastatin Market Forecast, 2009-2024
4.6.3 Zocor Market Forecast, 2009-2024
4.6.4 Generic Simvastatin Market Forecast, 2009-2024
4.7 Pravastatin
4.7.1 The Pravastatin Market in 2008
4.7.2 Pravastatin Market Forecast, 2009-2024
4.7.3 Mevalotin/Pravachol Market Forecast, 2009-2024
4.7.4 Generic Pravastatin Market Forecast, 2009-2024
4.8 Fluvastatin
4.8.1 The Fluvastatin Market in 2008
4.8.2 Fluvastatin Market Forecast, 2009-2024
4.8.3 Lescol/Lochol Market Forecast, 2009-2024
4.8.4 Generic Pravastatin Market Forecast, 2009-2024
4.9 Pitavastatin
4.9.1 The Pitavastatin Market in 2008
4.9.2 Pitavastatin Market Forecast, 2009-2024
4.10 Lovastatin
4.10.1 The Lovastatin Market in 2008
4.10.2 Lovastatin Market Forecast, 2009-2024
4.11 Statin/Non-Statin Combination Drugs
4.11.1 The Statin/Non-Statin Combination Drug Market in 2008
4.11.2 Launch of new Statin Combination Drugs Will Drive Growth During 2009-2014
4.11.3 Genericisation in the Statin/Non-Statin Combination Sector, 2014-2024
4.11.4 Vytorin/Inegy Market Forecast, 2009-2013
4.11.5 Vytorin/Inegy Market Forecast, 2014-2024
4.11.6 Caduet Market Forecast, 2009-2024
4.12 Leading Statin Manufacturers
4.12.1 Leading Statin Manufacturers, 2008: Seven Players Control 85% of the Market
4.12.2 Pfizer’s Statin Revenues Forecast, 2009-2014
4.12.3 A New Leading Statin Manufacturer by 2013
4.12.4 Merck & Co./Schering-Plough Statin Revenues Forecast, 2009-2014

5 Issues Affecting the Statin Industry
5.1 SWOT Analysis of the Statin Industry
5.2 Patient Compliance
5.2.1 Patients on Statins Exhibit Poor Patient Compliance
5.2.2 Effective Contact Between Patients and Healthcare Practitioners is the Key to Improving Patient Compliance
5.2.3 Developments in Cholesterol Testing
5.2.4 Diagnostic Testing for Genetic Markers May Increase Patient Compliance
5.2.5 Increasing Use of Web-Based Information Technology Will Improve Patient Compliance
5.3 Generic Statins
5.3.1 Expected Patent Expiries in the Statin Market
5.3.2 Governments and Insurers Will Favour Generic Statins
5.4 Statin Clinical Trials
5.5 Safety of Statins
5.6 Statin OTC Switching
5.6.1 The Rationale for OTC Switching
5.6.2 Statin OTC Switching in the UK
5.6.3 Statin OTC Switching in the US
5.6.4 What are the Worldwide Prospects for Statin OTC Switching?
5.7 Prevalence of Coronary Heart Disease
5.7.1 Coronary Heart Disease is the Leading Cause of Death Worldwide
5.7.2 Future Projections for Prevalence of Coronary Heart Disease
5.7.3 The Economic Cost of Coronary Heart Disease
5.8 Promising Non-Statin Lipid-Lowering Pipeline
5.8.1 Statins Cannot Treat All Forms of Dyslipidaemia
5.8.2 Developments in Existing Rivals for Statins
5.8.2.1 Novel Nicotinic Acid Formulations
5.8.2.2 New Formulation of Fibrates
5.8.2.3 Omega-3 Fatty Acids
5.8.2.4 Functional Foods and Nutritional Supplements
5.8.3 Novel Lipid-Lowering Agents
5.8.3.1 CETP Inhibitors
5.8.3.2 Cholesterol Absorption Inhibitors
5.8.3.3 Antisense Oligonucleotides
5.8.3.4 PPAR-Alpha Agonists
5.8.3.5 MTP Inhibitors
5.8.3.6 Phospholipase A2 Inhibitors
5.8.3.7 Nicotinic Acid Receptor Agonists
5.8.3.8 Human Antibodies

6 Expert Opinion on Methods to Improve Patient Compliance
6.1 Statin Patient Compliance: Humayun J. Chaudhry, D.O., M.S., FACP, Commissioner of Health Services, Suffolk County, New York
6.1.1 Improving Patient Compliance in Statin Therapy
6.1.2 The Future of Cholesterol Testing
6.1.3 Web-Based Information Technology in Statin Prescribing
6.2 Genetic Markers to Improve Patient Compliance: Thomas White, Ph.D., Chief Scientific Officer and Vice President of Research and David P. Speechly, PhD Vice President Corporate Affairs, Celera
6.2.1 Patient Compliance for Statins is Poor
6.2.2 Genetic Markers: The KIF6 Risk Allele
6.2.3 Genetic Markers Could Improve Patient Compliance
6.2.4 Diagnostic Tests for Genetic Markers
6.2.5 Evidence for Genetic Marker Tests Increasing Patient Compliance
6.2.6 Effect of Genetic Marker Diagnostic Effects on Future Statin Prescribing Patterns
6.2.7 The Future of Cholesterol Testing
6.2.8 Effect of Genetic Markers on Clinical Trials Involving Statins
6.2.9 Web-Based Technologies to Improve Patient Compliance

7 Statin Country Markets
7.1 Leading Country Markets in 2008
7.2 Leading Country-Market Forecasts, 2009-2024
7.3 The US Statin Market
7.3.1 The US Statin Market in 2008
7.3.2 US Statin Market Forecast, 2009-2014
7.3.3 US Statin Market Forecast, 2014-2024
7.4 The Japanese Statin Market
7.4.1 The Japanese Statin Market in 2008
7.4.2 Japanese Statin Market Forecast, 2009-2024
7.5 The Canadian Statin Market
7.6 European Statin Markets
7.7 Emerging Statin Markets: China and India

8 The Statin Pipeline
8.1 The Statin Pipeline Lacks New Products
8.2 New Statins and Statin Combination Drugs in Development
8.2.1 Crestor/TriLipix
8.2.2 Crestor for Patients with Elevated CRP
8.2.3 Simvastatin and Nicotinic Acid/Laropiprant
8.2.4 Pravastatin and Fenofibrate Combination Therapy
8.2.5 Simvastatin and Fenofibrate Combination Therapy
8.2.6 Vytorin for Kidney Disease and Acute Coronary Syndrome.
8.2.7 Simvastatin/Rosiglitazone
8.2.8 PPD Statin/RBx 10558
8.2.9 Simvastatin/Aspirin/Lisinopril/Hydrochlorothiazide
8.2.10 Simvastatin/Aspirin/Ramipril
8.2.11 NCX 6560
8.2.12 Atorvastatin/Ezetimibe

9 Conclusions
9.1 The Statin Market in 2008
9.2 Future Challenges for the Statin Industry
9.3 Rise of the Generics: World Statin Market Forecast, 2009-2024
9.4 Leading Statin Manufacturers and Country Markets

List of Tables
Table 2.1 Risk Levels for Total Cholesterol
Table 2.2 Risk Levels for LDL Cholesterol
Table 2.3 Risk Levels for HDL Cholesterol
Table 2.4 Risk Levels for Triglycerides
Table 2.5 The Fredrickson/WHO Classification of Dyslipidaemia
Table 3.1 Leading Generic Lovastatin Manufacturers
Table 3.2 Leading Generic Simvastatin Manufacturers
Table 3.3 Leading Generic Pravastatin Manufacturers
Table 3.4 Branded Fibrates
Table 3.5 Leading Prescription Omega-3 Acid Products
Table 4.1 World Lipid-Lowering Drug Market, 2008
Table 4.2 Non-Statin Lipid-Lowering Drug Market, 2008
Table 4.3 World Lipid-Lowering Drug Market Forecasts, 2009-2014
Table 4.4 World Lipid-Lowering Drug Market Forecasts, 2015-2024
Table 4.5 Leading Statin Types and Brands, 2008
Table 4.6 Statin Type Market Forecasts, 2009-2014
Table 4.7 Statin Type Market Forecasts, 2015-2024
Table 4.8 The Branded and Generic Statin Markets, 2008
Table 4.9 Branded and Generic Statin Market Forecasts, 2009-2014
Table 4.10 Branded and Generic Statin Market Forecasts, 2015-2024
Table 4.11 Atorvastatin Market, 2008
Table 4.12 Atorvastatin Drugs Forecasts, 2009-2014
Table 4.13 Atorvastatin Drugs Forecasts, 2015-2024
Table 4.14 Rosuvastatin Market, 2008
Table 4.15 Rosuvastatin Drugs Forecasts, 2009-2014
Table 4.16 Rosuvastatin Drugs Forecasts, 2015-2024
Table 4.17 Simvastatin Market, 2008
Table 4.18 Simvastatin Drugs Forecasts, 2009-2014
Table 4.19 Simvastatin Drugs Forecasts, 2015-2024
Table 4.20 Pravastatin Market, 2008
Table 4.21 Pravastatin Drugs Forecasts, 2009-2014
Table 4.22 Pravastatin Drugs Forecasts, 2015-2024
Table 4.23 Fluvastatin Market, 2008
Table 4.24 Fluvastatin Drugs Forecasts, 2009-2014
Table 4.25 Fluvastatin Drugs Forecasts, 2015-2024
Table 4.26 Pitavastatin Drugs Forecasts, 2009-2014
Table 4.27 Pitavastatin Drugs Forecasts, 2015-2024
Table 4.28 Lovastatin Drugs Forecasts, 2009-2014
Table 4.29 Lovastatin Drugs Forecasts, 2015-2024
Table 4.30 Statin and Statin/Non-Statin Combination Drug Sales, 2008
Table 4.31 Statin/Non-Statin Combination Drug Market, 2008
Table 4.32 Statin/Non-Statin Combination Drugs Forecasts, 2009-2014
Table 4.33 Statin/Non-Statin Combination Drugs Forecasts, 2015-2024
Table 4.34 Leading Statin Manufacturers, 2008
Table 4.35 Leading Statin Manufacturers’ Revenue Forecasts, 2009-2014
Table 5.1 SWOT Chart for the Statins Industry, 2009-2024
Table 5.2 Expected Statin Patent Expiry Dates, 2009-2024
Table 5.3 Novel Lipid-Lowering Drugs in Development
Table 7.1 Leading Statin Country Markets, 2008
Table 7.2 Leading Statin Country-Market Forecasts, 2009-2014
Table 7.3 Leading Statin Country Market Forecasts, 2015-2024
Table 8.1 The Statins Pipeline

List of Figures
Figure 4.1 World Lipid-Lowering Drug Market, 2008
Figure 4.2 World Lipid-Lowering Drug Market Forecast, 2009-2024
Figure 4.3 Statin Type Market Share, 2008
Figure 4.4 Leading Statin Brand Market Share, 2008
Figure 4.5 World Statin Market Forecast, 2009-2024
Figure 4.6 Statin Type Market Forecast, 2009-2024
Figure 4.7 Statin Type Market Share, 2014
Figure 4.8 Statin Type Market Share, 2019
Figure 4.9 Statin Type Market Share, 2024
Figure 4.10 Branded and Generic Statin Market Forecasts, 2009-2024
Figure 4.11 Atorvastatin Drugs Forecasts, 2009-2024
Figure 4.12 Rosuvastatin Drugs Forecasts, 2009-2024
Figure 4.13 Simvastatin Drugs Forecasts, 2009-2024
Figure 4.14 Pravastatin Drugs Forecasts, 2009-2024
Figure 4.15 Fluvastatin Drugs Forecasts, 2009-2024
Figure 4.16 Pitavastatin Drugs Forecasts, 2009-2024
Figure 4.17 Lovastatin Drugs Forecasts, 2009-2024
Figure 4.18 Statin Combination Drugs Forecasts, 2009-2024
Figure 4.19 Leading Statin Manufacturers, 2008
Figure 4.20 Leading Statin Manufacturers’ Revenue Forecasts, 2009-2014
Figure 7.1 Statin Market Share by Country, 2008
Figure 7.2 Statin Market Share by Country, 2014
Figure 7.3 Statin Market Share by Country, 2019
Figure 7.4 Statin Market Share by Country, 2024
Figure 7.5 US Statin Market Forecast, 2009-2024
Figure 7.6 Japanese Statin Market Forecast, 2009-2024
Figure 7.7 Canadian Statin Market Forecast, 2009-2024
Figure 7.8 French, UK, Chinese and Indian Statin Market Forecasts, 2009-2024
Figure 9.1 World Statin Market Forecast, 2009-2024

Companies Listed

Abbott
Actavis
Aegerion
Almirall
Alter [Spain]
Amarin
American Heart Association
American Medical Association [US]
Apotex
Arena Pharmaceuticals [US]
Astellas
AstraZeneca
Atherotech
Bagó [Argentina]
Bayer
Berkeley HeartLab (part of Celera)
BioInvent [Sweden]
Bristol-Myers Squibb
Celera
Center for Cardiovascular Disease in Women at Brigham and Women's Hospital
Centro Nacional de Investigaciones Cardiovasculares (National Centre for Cardiovascular Research, CNIC) [Spain]
Chiesi
Choongwae [South Korea]
CINFA [Spain]
Cobalt Laboratories
Cobalt Pharmaceuticals
Covidien
Daiichi Sankyo
Dr. Reddy's Laboratories
European Medicines Agency (EMEA)
European Society of Cardiology
Ferrer
Food and Drug Administration (FDA)
Galephar Pharmaceutical Research
Gedeon Richter
Genentech
Genfit
Genzyme
GlaxoSmithKline (GSK)
Human Genome Sciences (HGS)
Intas
Isis
Japan Tobacco
Johnson & Johnson
Kissei
Kowa
Krka
Kyorin
LifeCycle Pharma
Liposcience
Lupin
Medicines and Healthcare products Regulatory Agency (MHRA) [UK]
Medley [Brazil]
Menarini
Merck & Co.
Merck/Schering-Plough Pharmaceuticals [joint venture between Merck & Co. and Schering-Plough]
Micro Labs
Mitsubishi Tanabe
Mochida
Mylan
Nichi-Iko [Japan]
NicOx
Nissan Chemical
Novartis
Par
Pfizer
Pharmaceutical Product Development (PPD)
Pierre Fabre
Polpharma
Public Citizen [US]
Ranbaxy
Ratiopharm
Recordati
Roche
Sanofi-Aventis
Sawai [Japan]
Schering-Plough
Sciele [wholly owned subsidiary of Shionogi]
Sepracor
Servier
Shionogi
Sigma Pharmaceuticals [Australia]
Sigma-Tau
SkyePharma
Solvay
Stada
Teva
University of Auckland
Watson
World Health Organization (WHO)
Zentiva
Zydus Cadila

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REPORT

Statins: The World Market, 2009-2024

Report Details

Table of Contents

Companies Listed