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CONFERENCE

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6th Annual Biosimilars Conference

6th Annual Biosimilars Conference

Revolutionizing biosimilars market - debates, challenges and innovations

2nd - 4th March 2010, Boston Harbor Hotel at Rowes Wharf, Boston, USA

  1. Background Info
  2. Workshop
  3. Day 1
  4. Day 2
  5. Partners
  6. Past Papers
Junior Sponsor
  • PAREXEL Consulting
Media Partners
  • PharmiWeb.com
  • BIOTECHNOLOGY EUROPE
  • Future Pharmaceuticals
  • InPharm
  • Pharma Connections Worldwide
Discussion Groups
  • LinkedIn

Background Info

Key Speakers
• Tina S. Morris, Vice President, Biologics and Biotechnology, United States Pharmacopeial Convention
• Dr. Yining Zhao, Associate Research Fellow, Strategy Management Group, Pfizer
• Les Jordan, CTO, Life Sciences Industry Unit, Microsoft
• Terry Hisey, Vice Chairman, U.S. Life Sciences Leader, Deloitte LLP
• James Harris, CEO, Healthcare Economics LLC
• Mateja Urlep, Founder & CEO, TikhePharma
• Dr Duu-Gong Wu, Executive Director, Pharmanet
• Timothy J. Shea, Jr., Director, Sterne, Kessler, Goldstein & Fox
• Dr. Fethi Trabelsi, Director, Scientific & Regulatory Affairs, Anapharm
• Roger Lias, President, Eden Biodesign
• Dr. Terry Surowy, Research Manager, Bioassays, Promega Corporation
• Ana T. Menendez Ph.D., Senior Director of Biotechnology, Catalent Pharma Solutions
• Dr Frank Moffatt, Product Manager Biopharmaceutical and DNA Analysis, Solvias
• Dr. Saurabh Aggarwal, Principal Consultant, Reimbursement and Market Access, PAREXEL Consulting
• Dr. Bruce Babbitt, Principal Consultant, Biotechnology, PAREXEL Consulting  

"The US biosimilar market, generating $0.06bn sales in 2008, will achieve significant revenues only after expected implementation of a biosimilar regulatory pathway in 2013, visiongain predicts. If this occurs, the US biosimilar market will increase to annual revenues of $1.95bn in 2014" (Source: Visiongain Report ‘Biosimilars and Follow-on Biologics 2009-2024’ Published: April 2009

Biologics constitutes a major share of expenditure in the USA and globally. It is one of the fastest growing sectors of the pharmaceutical industry which corresponds to over 15% of the total pharmaceutical market.

There is a large and potentially lucrative demand for lower cost biological drugs worldwide. With favourable regulatory developments, the biosimilar sector should pick up significantly, however, forming an important developing pharma market.

Visiongain's 6th Annual Biosimilars Conference will feature keynote addresses, presentations, case studies and interactive discussions from regulatory issues to manufacturing process, clinical assessment, commercialization and pricing.

This three day event is an ideal forum for experts from the industry and academy sector together to discuss and share their experience and best practices.

Why Attend?
• Discover the key strategies for process development/manufacturing of biosimilars
• Discuss the key regulatory and scientific issues of biosimilars and follow-on biologics
• Examine commercialisation of biosimilars
• Understand the development and marketing of biosimilars
• Assessing impact of IT driven patient adherence methodologies on biologics and biosimilars
• Learn how to develop and create strategic outsourcing strategies for biosimilars
• Network and discuss ideas with the leaders in the field

Who should attend?
Branded Biotechnology, Pharmaceuticals & Generic Pharmaceutical Companies, Drug Regulators, Healthcare Agencies, Government Departments, Contract Research/Bio manufacturing, Organisations, Regulatory Affairs, Pharmacovigilance

VPs, Directors, Heads, Managers of:
• Follow on Biologics/Follow on Proteins/Biosimilars
• Biologics/Biotechnology/ Biogenerics
• Legal Affairs
• Intellectual Property
• Health Economics
• Pricing and Reimbursement
• Biopharmaceuticals/ Biotherapeutics
• Clinical Immunology
• Principal Scientist
• Payers
• Chief Scientific Officer
• Process Control and Analytical Technologies
• Analytical Characterisation
• Regulatory Compliance
• Pharmacovigilance
• Drug Safety & Risk Management
• Quality Affairs/ Quality Control
• New Product Development
• Process Science
• Portfolio Management
• Research & Development
• Business Development
• Business Operations
• Scientific Affairs
• Commercial Affairs
• Marketing 

Venue
Boston Harbor Hotel at Rowes Wharf, 70 Rowes Wharf, Boston, MA 02110
Phone: 617.439.7000, Fax: 617.330.9450, www.bhh.com
Guest Room Reservations: 800.752.7077, Email: reservations@bhh.com

Discounted accommodation is available for Visiongain attendees at the Boston Harbor Hotel at Rowes Wharf for $225 plus taxes per guest room per night. Reservations can be made by calling (800) 752-7077 and referencing the code: Visiongain, for the special group room block. Failure to cancel a reservation 24 hours prior to the arrival date will result in a charge of one night’s room and tax to your credit card. This offer is subject to room availability. 

Workshop

Pre-Conference Interactive Workshop, Tuesday 2nd March 2010, Boston, USA

Creating confidence in a new wave of biologics therapy - Overcoming barriers to entry 

Led by: Gil Bashe, Executive Vice President, Makovsky + Co
Brian E. Harvey, MD, PhD, Vice President, Regulatory Policy, sanofi-aventis
Kristie Kuhl, JD, Senior Vice President, Makovsky + Company
Francis B. Palumbo, PhD, JD, Professor and Executive Director, University of Maryland School of Pharmacy Center on Drugs and Public Policy

Timings: 09:30 - 10:00 Coffee & Registration
10:00 - 15:00 Workshop
Timing includes lunch and refreshment breaks

Agenda:
Legislative pathways for biosimilar regulatory approval may provide significant implementation confusion. The wrong path to biosimilar approval may jeopardize ability to develop future advancements and place obstacles in the path to reducing healthcare costs. The debate on whether legislation is pro-innovator or biogenerics entrepreneur may overshadow addressing key concerns for future success. This workshop will summarize the key concerns and enable participants to tackle these issues. Discussions include:
• How much authority will FDA have to make case-by-case approval decisions?
• What should the clinical data requirements be for approval, immunogenicity and subsequent interchangeability?
• Class and product-specific naming
• How should market exclusivity address ever greening?
• How does patent law affect FOBs entry into the market?
• What should the nomenclature system be to reduce confusion and promote patient safety? 

About your workshop leaders:

Gil Bashe, Executive Vice President, Makovsky + Co
Workshop Leader

Mr. Bashe is counselor to pharmaceutical, biotechnology, medical-device manufacturers and patient advocacy groups. He has advised clients on follow-on-biologic (FOB) policies and reimbursement, first in Europe and now in the United States. Mr. Bashe is a limited partner with GTCR Golder Rauner, one of the nation’s leading private-equity firms and was CEO of CommonHealth, a WPP Group company, having served as at sister-company Hill and Knowlton as Worldwide Health Practice director overseeing policy, provider and product communications.

Brian E. Harvey, MD, PhD, Vice President, Regulatory Policy, sanofi-aventis
Dr. Harvey leads the sanofi-aventis Corporate Regulatory Affairs (CRA) office in Bethesda, Maryland and interacts with the Food and Drug Administration (FDA), C-Path Institute and key industry representatives on behalf of sanofi-aventis. He represents sanofi on PhRMA, Regulatory Affairs Coordination Committee, and BIO’s Regulatory Affairs Committee. Prior to joining sanofi, Dr. Harvey worked at the FDA in CDRH, CBER and CDER centers for more than 11 years and worked on health issues in the U.S. Senate. Dr. Harvey completed his Ph.D. in biochemistry and his M.D. degree at the University of Connecticut.

Kristie Kuhl, JD, Senior Vice President, Makovsky + Company
Kristie Kuhl provides counsel on issues that impact biotechnology, specialty pharma, dietary supplements and medical devices. Her legal and communication skills provide keen insight in bringing together communities with diverse interests especially important in the FOB arena. She has provided counsel on the issues surrounding biosimilar approvals in Europe including communicating the differences between biosimilars and generic drugs.

Francis B. Palumbo, PhD, JD, Professor and Executive Director, University of Maryland School of Pharmacy Center on Drugs and Public Policy
Dr. Francis Palumbo is both a lawyer and registered pharmacist and approaches biosimilars with a unique perspective. He has a strong interest in pharmacy and food and drug law, pharmacoeconomics, pharmacoepidemiology and health services research. As an adjunct professor at the Maryland School of Law, he teaches a course in food and drug law, including content on foods, dietary supplements, drugs and other products regulated by the FDA and its sister agencies. Dr. Palumbo received his B.S. in Pharmacy from the Medical University of South Carolina, M.S. and Ph.D. in Health Care Administration from the University of Mississippi and J.D. from the University of Baltimore Law Center.

About: Makovsky + Co
Founded in 1979, Makovsky + Company is today one of the nation’s leading independent global public relations consultancies. The firm attributes its success to its original vision: that the Power of Specialized ThinkingTM is the best way to build reputation, sales and fair valuation for a client. Celebrating its 30th year in 2009, Makovsky has received numerous industry accolades including; the American Business Awards 2009 PR Agency of the Year and Holmes Report 2009 Multispecialist Agency of the Year. Based in New York City, the firm has agency partners in more than 26 countries and in 35 U.S. cities through IPREX, the third largest worldwide public relations agency partnership, of which Makovsky is a founder.
For further information, please visit: www.makovsky.com 

Day 1

Day 1, Wednesday 3rd March 2010, Boston, USA

09:30 Registration and refreshments

10:00 Opening address from the chair

James Harris
CEO
Healthcare Economics LLC

10:10 Opportunities and challenges for biosimilars in the global market
• Assessing the promise and potential for biosimilars
• Latest progress in biosimilars development
• Regulatory update on bioequivalence, interchangeability and substitution for biosimilars
• Provider perspectives and acceptance of biosimilars
• Payer perspectives and formulary acceptance
• Examining the viability of biosimilars & ROI considerations

James Harris
CEO
Healthcare Economics LLC

10:50 Presentation to be announced

11:30 Morning refreshments

11:50 Demystifying the market aspects/implications of follow on biologics
• Market positioning and attractiveness
• Strategies
• Commercial operations

R.T. (Terry) Hisey
Vice Chairman and U.S. Life Sciences Leader
Deloitte LLP

12:30 CMC Analysis: The Foundation of Success in Biosimilar Development & Commercialization
• Overview of biosimilars regulations in EU (current) & in US (pending)
• CMC analytical requirements - practical & commercial implications
• Important differences between "generics" & "biosimilars"
• Case studies illustrating the critical aspects of CMC analysis
• Opportunities for Biosimilar development
• Strategies for mitigation of the risks involved

Dr Frank Moffatt
Product Manager Biopharmaceutical and DNA Analysis
Solvias

13:10 Networking lunch

14:30 The impact of a patient centric viewpoint on biosimilars
• Review of emerging PHR and patient centric healthcare information technology (HIT) and how it applies to biosimilars
• Includes a discussion of the effect of IT driven patient adherence methodologies on biologics and biosimilars

Les Jordan
CTO, Life Sciences Industry Unit
Microsoft

15:10 Strategies for process development/manufacturing of biosimilars (for global markets)
• The biosimilar CMC section - what does it look like?
• Where (if anywhere) can time be saved when developing a biosimilar production process?
• Derivation of cell lines and materials
• The importance of analytics and comparability protocols
• Early mistakes can be expensive - what to be aware of

Dr. Roger Lias
President
Eden Biodesign

15:50 Afternoon refreshments

16:10 Bioassays for biosimilars
• Bioassay needs for biosimilars
• Advancements in bioassay development
• Case study: TNFa blocker bioassays

Dr. Terry Surowy
Research Manager, Bioassays
Promega Corporation

16:40 Immunogenicity Programs - Not just another box to check
• Development of a risk assessment strategy
• Minimum expectations of immunogenicity methods
• Phase and risk appropriate design of sample sampling
• Productive integration of immunogenicity results into clinical trials

Ana T. Menendez Ph.D.
Senior Director of Biotechnology
Catalent Pharma Solutions

17:20 Closing remarks from the chair

17:25 Networking drinks
Take your discussions further and build new relationships in a relaxed and informal setting 

Day 2

Day 2, Thursday 4th March 2010, Boston, USA

09:30 Registration and refreshments

10:00 Opening address from the chair

10:10 Role of USP standards in the quality assessment of biological medicines
• Role of the official compendial and standard-setting process
• Value of public standards and monographs
• Quality assessment of biological medicines
• Analytical challenges and future developments

Tina S. Morris
Vice President, Biologics and Biotechnology
United States Pharmacopeial Convention

10:50 An overview on regulatory and scientific issues of biosimilars and follow-on biologics
• Updates on regulatory and, scientific issues related to biosimilars and follow-on biologics
• Discussions on technical challenges for the approval of biosimilars/follow-on biologics
• Requirements of CMC, pre-clinical and clinical studies using examples of approved products in both US and Europe

Dr. Duu-Gong Wu
Executive Director, Consulting Division
PharmaNet

11:30 Morning refreshments

11:50 Legislative and regulatory developments impacting the biologics and biosimilars marketplace
• Update on progress of biosimilars legislation through the U.S. House and Senate
• Analysis of the provisions of the competing U.S. bills
• Comparison of the proposed biosimilars legislation to small molecule regulation under Hatch-Waxman
• Views of affected constituencies (biopharma companies, generics companies, health care providers, patients)
• Comparison of the proposed US regulatory scheme to those in other parts of the world (especially Europe and Japan)

Timothy J. Shea, Jr.
Director
Sterne, Kessler, Goldstein & Fox

12:30 Trends and technical challenges for the development of biosimilars in China
• Understanding the current competitive landscaping of China’s biosimilars market
• Addressing the critical issues and gaps of China’s biologics R&D and manufacturing capabilities
• Discussing the trends and opportunities of the biosimilars/biobetters in China

Dr. Yining Zhao
Associate Research Fellow, Strategy Management Group
Pfizer

Dr. James Leung
Principal Consultant
J. Leung

13:10 Networking lunch

14:30 Follow-on Biologics (Biosimilars) development with approval and market access in mind
• Market assessment, market saturation, and market access and reimbursement considerations when deciding upon candidate selection, feasibility and planning
• Scientific, regulatory, clinical and safety aspects of development strategies
• Planning for FOBs 

Dr. Saurabh Aggarwal
Principal Consultant, Reimbursement and Market Access
PAREXEL Consulting

Dr. Bruce Babbitt
Principal Consultant, Biotechnology
PAREXEL Consulting

15:10 Biosimilars - Succeeding in the market of the future
• From dream to reality
• The global biosimilars market today
• Lessons learned so far
• Evolving business models
• Delivering against the promise?

Mateja Urlep
Founder & CEO, TikhePharma
Former Global Head of Marketing and Medical, Sandoz

15:50 Afternoon refreshments

16:10 Clinical Phase 1 PK/PD trials for biosimilar/follow-on products
• The clinical comparability exercise
• PK/PD studies for early efficacy and safety assessment
• Study design challenges with some particular specific biosimilars

Dr. Fethi Trabelsi
Director, Scientific & Regulatory Affairs
Anapharm

16:50 Chair’s closing remarks

17:00 End of Conference 

Partners

Junior Sponsor:

PAREXEL Consulting
PAREXEL Consulting provides integrated product development consulting services, helping biopharmaceutical and medical device companies shorten time to market and maintain product viability for the long-term. Through our unique fusion of scientific, regulatory, and business expertise, we also help clients manage risk, and maximize product and portfolio value at every milestone and phase of development worldwide.
PAREXEL Consulting leads in the development of Follow-on Biologics (FOB), having played an integral role in bringing the first biosimilars to the EU market. To help propel your advantage on the cutting edge of this market, PAREXEL Consulting provides unparalleled expertise from renowned medical doctors, scientists covering all key disciplines, regulatory experts including former FDA and EU regulators, market and reimbursement specialists, and statisticians and clinical research experts.
With our strong global presence, we can help you capitalize with a comprehensive, program for the selection, development and approval of any type of Follow-on Biologic product, any where in the world.
For further information, please visit www.parexelconsulting.com

Media Partners:

PharmiWeb.com
PharmiWeb.com is the leading industry-sponsored portal for the pharmaceutical sector. Supported by most of the leading pharmaceutical corporations, PharmiWeb.com provides dynamic real-time news, features, events listings and international jobs to industry professionals across Europe and the US. For further information please email: corporate@pharmiweb.com 

BIOTECHNOLOGY EUROPE
BIOTECHNOLOGY EUROPE is owned by BIOTECHNOLOGY WORLD. It is based and located in Warsaw, Poland. Biotechnology World was founded in 2007 to provide the world’s biotech and pharma information and market to make it universally accessible and useful for scientific and business processes. Its first step to fulfilling that mission was building the BIOTECHNOLOGY EUROPE platform that will allow a quick spread of information in different channels. BIOTECHNOLOGY EUROPE offers companies completed internet public relations, publication and marketing solutions. One of the main goals of BIOTECHNOLOGY EUROPE is to integrate the Biotech and Pharma Sector in Europe to global biotechnology, pharmaceutical and life science activities. For further information please visit www.biotechnology-europe.com 

Future Pharmaceuticals
Future Pharmaceuticals has forged powerful relationships with key industry leaders to provide a platform for successful brand recognition, and for senior decision-makers to have the means to procure and plan implementation strategies based on the topics covered. Positioned to be an authoritative resource within top pharma companies as well as small, specialty, and biotech, Future Pharmaceuticals magazine is geared to create a deep penetration into a highly targeted and responsive audience, bridging the gap between the industries' top issues and the solutions top-tier vendors can provide. For further information, please visit www.futurepharmaus.com 

InPharm
InPharm is the online platform for exclusive pharmaceutical news, comment, contracts, services, jobs and events and is home to InPharmjobs.com, Pharmafile and Pharmafocus. For further information please visit: www.In-Pharm.com 

Pharma Connections Worldwide
Pharma Connections Worldwide® is the leading professional business networking website focused in the Pharmaceutical, Biotechnology and Life Sciences research industry. Our goal is to provide a conduit for delivery of premiere content coupled with the right clientele in order to facilitate business development opportunities among industry professionals responsible for making key decisions in a global marketplace. For further information please visit www.pharmaconnections.com

Enquiries

If you would like more information on the range of sponsorship or exhibition possibilities for visiongain's 6th Annual Biosimilars Conference, please contact:
Avnee Gajjar, +44 (0)20 7549 9948
avnee.gajjar@visiongainglobal.com
Henry James, +44 (0) 0207 549 9942
henry.james@visiongainglobal.com
Ronald Magali, +44 (0)20 7549 9934
ronald.magali@visiongainglobal.com

Past Papers

Speaker presentations are free to delegates. If you are unable to attend the event, the presentations are published two weeks after the event and are available to purchase.